• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

有机二次离子质谱：水蒸气注入的信号增强。

Organic secondary ion mass spectrometry: signal enhancement by water vapor injection.

机构信息

Institute of Condensed Matter and Nanosciences–Bio and Soft Matter (IMCN/BSMA), Université catholique de Louvain, Louvain-la-Neuve, Belgium.

出版信息

J Am Soc Mass Spectrom. 2010 Dec;21(12):2005-10. doi: 10.1016/j.jasms.2010.08.013. Epub 2010 Aug 27.

DOI:10.1016/j.jasms.2010.08.013
PMID:20864353
Abstract

The enhancement of the static secondary ion mass spectrometry (SIMS) signals resulting from the injection, closely to the sample surface, of H(2)O vapor at relatively high-pressure, was investigated for a set of organic materials. While the ion signals are generally improved with increasing H(2)O pressure upon 12 keV Ga(+) bombardment, a specific enhancement of the protonated ion intensity is clearly demonstrated in each case. For instance, the presence of H(2)O vapor induces an enhancement by one order of magnitude of the M + H static SIMS intensity for the antioxidant Irgafos 168 and a ∼1.5-fold increase for polymers such as poly(vinyl pyrrolidone).

摘要

研究了在相对高压下将 H(2)O 蒸汽注入到样品表面附近对一组有机材料的静态二次离子质谱 (SIMS) 信号的增强作用。虽然在 12keV Ga(+) 轰击时，随着 H(2)O 压力的增加，离子信号通常会增强，但在每种情况下都清楚地证明了质子化离子强度的特定增强。例如，H(2)O 蒸汽的存在会使抗氧化剂 Irgafos 168 的M+H静态 SIMS 强度增强一个数量级，而对于聚合物如聚乙烯吡咯烷酮则会增加约 1.5 倍。

相似文献

1
Organic secondary ion mass spectrometry: signal enhancement by water vapor injection.有机二次离子质谱：水蒸气注入的信号增强。
J Am Soc Mass Spectrom. 2010 Dec;21(12):2005-10. doi: 10.1016/j.jasms.2010.08.013. Epub 2010 Aug 27.
2
Matrix-free high-resolution imaging mass spectrometry with high-energy ion projectiles.使用高能离子射弹的无基质高分辨率成像质谱分析
J Mass Spectrom. 2009 Jan;44(1):128-36. doi: 10.1002/jms.1482.
3
Comparative study of organic dyes with time-of-flight static secondary ion mass spectrometry and related techniques.有机染料的飞行时间静态二次离子质谱及相关技术的比较研究。
J Mass Spectrom. 2005 May;40(5):615-27. doi: 10.1002/jms.832.
4
Effects of cryogenic sample analysis on molecular depth profiles with TOF-secondary ion mass spectrometry.低温样品分析对飞行时间二次离子质谱分子深度剖面的影响。
Anal Chem. 2010 Oct 1;82(19):8291-9. doi: 10.1021/ac101746h.
5
Improving secondary ion mass spectrometry C60(n+) sputter depth profiling of challenging polymers with nitric oxide gas dosing.采用一氧化氮气体注入的方法提高二次离子质谱 C60(n+) 溅射深度剖析技术在分析具有挑战性的聚合物时的性能。
Anal Chem. 2013 May 21;85(10):5064-70. doi: 10.1021/ac4003535. Epub 2013 May 8.
6
Improved molecular imaging in rodent brain with time-of-flight-secondary ion mass spectrometry using gas cluster ion beams and reactive vapor exposure.使用气体团簇离子束和反应性蒸汽暴露的飞行时间二次离子质谱法改善啮齿动物大脑中的分子成像。
Anal Chem. 2015 Apr 21;87(8):4305-13. doi: 10.1021/ac504774y. Epub 2015 Apr 2.
7
Application of a Gas-Injection System during the FIB-TOF-SIMS Analysis-Influence of Water Vapor and Fluorine Gas on Secondary Ion Signals and Sputtering Rates.气体注入系统在聚焦离子束飞行时间二次离子质谱分析中的应用——水蒸气和氟气对二次离子信号及溅射速率的影响
Anal Chem. 2019 Sep 17;91(18):11712-11722. doi: 10.1021/acs.analchem.9b02287. Epub 2019 Sep 3.
8
Organic secondary ion mass spectrometry: sensitivity enhancement by gold deposition.有机二次离子质谱法：通过金沉积提高灵敏度。
Anal Chem. 2002 Oct 1;74(19):4955-68. doi: 10.1021/ac020125h.
9
Metal-assisted secondary ion mass spectrometry: influence of Ag and Au deposition on molecular ion yields.
Anal Chem. 2004 Nov 15;76(22):6777-85. doi: 10.1021/ac049108d.
10
Preliminary evaluation of an SF5+ polyatomic primary ion beam for analysis of organic thin films by secondary ion mass spectrometry.用于通过二次离子质谱分析有机薄膜的SF5 +多原子一次离子束的初步评估。
Rapid Commun Mass Spectrom. 1998;12(19):1303-12. doi: 10.1002/(SICI)1097-0231(19981015)12:19<1303::AID-RCM330>3.0.CO;2-7.

引用本文的文献

1
(CO), (HO), and (HO) (CO) gas cluster ion beam secondary ion mass spectrometry: analysis of lipid extracts, cells, and Alzheimer's model mouse brain tissue.(CO), (HO), 和 (HO) (CO) 气体团簇离子束二次离子质谱法：脂质提取物、细胞和阿尔茨海默病模型鼠脑组织分析。
Anal Bioanal Chem. 2021 Jul;413(16):4181-4194. doi: 10.1007/s00216-021-03372-x. Epub 2021 May 11.
2
Quantifying SIMS of Organic Mixtures and Depth Profiles-Characterizing Matrix Effects of Fragment Ions.定量分析有机混合物和深度剖面的二次离子质谱-碎片离子的基质效应表征。
J Am Soc Mass Spectrom. 2019 Feb;30(2):309-320. doi: 10.1007/s13361-018-2086-8. Epub 2018 Oct 23.
3

本文引用的文献

1
Matrix-enhanced secondary ion mass spectrometry:  a method for molecular analysis of solid surfaces.基质增强二次离子质谱法：一种用于固体表面分子分析的方法。
Anal Chem. 1996 Mar 1;68(5):873-82. doi: 10.1021/ac950717i.
2
Influence of the organic layer thickness in (metal-assisted) secondary ion mass spectrometry using Ga+ and C60+ projectiles.（金属辅助）二次离子质谱法中有机层厚度对 Ga+和 C60+ 离子束的影响。
J Am Soc Mass Spectrom. 2009 Dec;20(12):2294-303. doi: 10.1016/j.jasms.2009.08.022. Epub 2009 Sep 3.
3
17O NMR investigation of phosphite hydrolysis mechanisms.
Molecular imaging of biological tissue using gas cluster ions.
使用气体团簇离子对生物组织进行分子成像。
Surf Interface Anal. 2014 Nov;46(1):115-117. doi: 10.1002/sia.5509.
4
A mixed cluster ion beam to enhance the ionization efficiency in molecular secondary ion mass spectrometry.一种用于提高分子二次离子质谱中电离效率的混合簇离子束。
Rapid Commun Mass Spectrom. 2014 Feb 28;28(4):396-400. doi: 10.1002/rcm.6793.
5
Enhancing secondary ion yields in time of flight-secondary ion mass spectrometry using water cluster primary beams.采用水簇团初级束提高飞行时间-二次离子质谱中的二次离子产率。
Anal Chem. 2013 Jun 18;85(12):5654-8. doi: 10.1021/ac4013732. Epub 2013 May 31.
6
Mass spectrometry imaging and profiling of single cells.单细胞的质谱成像和分析。
J Proteomics. 2012 Aug 30;75(16):5036-5051. doi: 10.1016/j.jprot.2012.03.017. Epub 2012 Mar 29.
7
Label free biochemical 2D and 3D imaging using secondary ion mass spectrometry.利用二次离子质谱进行无标记生物化学 2D 和 3D 成像。
Curr Opin Chem Biol. 2011 Oct;15(5):733-40. doi: 10.1016/j.cbpa.2011.05.016. Epub 2011 Jun 12.
亚磷酸酯水解机理的¹⁷O核磁共振研究。
Magn Reson Chem. 2007 Dec;45(12):1022-6. doi: 10.1002/mrc.2094.
4
Is proton cationization promoted by polyatomic primary ion bombardment during time-of-flight secondary ion mass spectrometry analysis of frozen aqueous solutions?在冷冻水溶液的飞行时间二次离子质谱分析过程中，多原子一次离子轰击会促进质子阳离子化吗？
Rapid Commun Mass Spectrom. 2006;20(8):1327-34. doi: 10.1002/rcm.2446.
5
Gold-enhanced biomolecular surface imaging of cells and tissue by SIMS and MALDI mass spectrometry.通过二次离子质谱（SIMS）和基质辅助激光解吸电离质谱（MALDI）对细胞和组织进行金增强生物分子表面成像。
Anal Chem. 2006 Feb 1;78(3):734-42. doi: 10.1021/ac0513111.
6
Proton transfer in time-of-flight secondary ion mass spectrometry studies of frozen-hydrated dipalmitoylphosphatidylcholine.冷冻水合二棕榈酰磷脂酰胆碱的飞行时间二次离子质谱研究中的质子转移
Anal Chem. 2003 Aug 15;75(16):4087-94. doi: 10.1021/ac026353t.
7
Probing cell chemistry with time-of-flight secondary ion mass spectrometry: development and exploitation of instrumentation for studies of frozen-hydrated biological material.用飞行时间二次离子质谱法探测细胞化学：用于研究冷冻水合生物材料的仪器的开发与应用
Rapid Commun Mass Spectrom. 2003;17(19):2163-7. doi: 10.1002/rcm.1169.
8
Time-of-flight secondary ion mass spectrometry: techniques and applications for the characterization of biomaterial surfaces.飞行时间二次离子质谱：用于生物材料表面表征的技术与应用
Biomaterials. 2003 Sep;24(21):3635-53. doi: 10.1016/s0142-9612(03)00159-5.
9
A C60 primary ion beam system for time of flight secondary ion mass spectrometry: its development and secondary ion yield characteristics.用于飞行时间二次离子质谱的C60一次离子束系统：其发展及二次离子产率特性
Anal Chem. 2003 Apr 1;75(7):1754-64. doi: 10.1021/ac026338o.
10
Organic secondary ion mass spectrometry: sensitivity enhancement by gold deposition.有机二次离子质谱法：通过金沉积提高灵敏度。
Anal Chem. 2002 Oct 1;74(19):4955-68. doi: 10.1021/ac020125h.