Department of Anaesthesia, Vakif Gureba Education and Teaching Hospital, Istanbul, Turkey.
Eur J Anaesthesiol. 2010 Nov;27(11):947-9. doi: 10.1097/EJA.0b013e32833e2656.
Difficult tracheal intubation following induction of general anaesthesia for caesarean section is a cause of morbidity and mortality. Our aim was to evaluate five bedside predictors that might identify women with potential intubation difficulty immediately prior to emergency caesarean section.
Women requiring emergency caesarean section with general anaesthesia and tracheal intubation who had been assessed by the same experienced anaesthesiologist preoperatively were included in this study. Mallampati score, sternomental distance, thyromental distance, interincisor gap and atlantooccipital extension were all measured. The same anaesthesiologist performed laryngoscopy and graded the laryngeal view according to Cormack and Lehane. Exact logistic regression was used to identify significant independent predictors for difficult intubation (Cormack and Lehane grades ≥ 3) with two-sided P value less than 0.05 considered as significant.
In 3 years, 239 women were recruited. Cormack and Lehane grades of 2 or less (easy) were found in 225 and grade of at least 3 (difficult) in 14 women. Patients' characteristics (age, height, weight, BMI or weight gain) were not significantly associated with difficulty of intubation. The incidence of difficult intubation was 1/17 women [95% confidence interval (CI) from 1/31 to 1/10]. A positive result from any of the five predictors combined had a sensitivity of 0.21 (95%CI 0.05-0.51), a specificity of 0.92 (95%CI 0.88-0.96), a positive predictive value of 0.15 (95%CI 0.032-0.38) and a negative predictive value of 0.95 (95%CI 0.91-0.97) for a Cormack and Lehane grade of at least 3 at laryngoscopy.
Airway assessment using these tests cannot be relied upon to predict a difficult intubation at emergency caesarean section as the low sensitivity means that 79% (95%CI 49-95) of difficult intubations will be missed.
全麻下剖宫产诱导后困难气管插管是发病率和死亡率的一个原因。我们的目的是评估 5 种床边预测指标,以便在紧急剖宫产前即刻识别可能存在插管困难的女性。
本研究纳入了经同一位有经验的麻醉医师术前评估后需行紧急剖宫产全麻气管插管的患者。测量了 Mallampati 评分、胸骨上切迹至下颌骨距离、甲状软骨切迹至下颌骨距离、门齿间距和寰枕关节伸展度。同一位麻醉医师进行喉镜检查,并根据 Cormack 和 Lehane 分级对喉像进行分级。采用精确逻辑回归确定困难插管(Cormack 和 Lehane 分级≥3)的显著独立预测因素,双侧 P 值小于 0.05 为显著。
3 年来,共纳入 239 名女性。225 名患者的 Cormack 和 Lehane 分级为 2 级或更低(容易),14 名患者的分级为至少 3 级(困难)。患者特征(年龄、身高、体重、BMI 或体重增加)与插管困难无显著相关性。困难插管的发生率为每 17 名女性中有 1 名(95%CI 1/31 至 1/10)。五种预测指标中的任何一种阳性结果的敏感度为 0.21(95%CI 0.05-0.51),特异度为 0.92(95%CI 0.88-0.96),阳性预测值为 0.15(95%CI 0.032-0.38),阴性预测值为 0.95(95%CI 0.91-0.97),预测 Cormack 和 Lehane 分级至少为 3 级的喉镜检查。
使用这些测试进行气道评估不能用于预测紧急剖宫产时的困难插管,因为低敏感度意味着 79%(95%CI 49-95)的困难插管将被漏诊。