National Center for PTSD VA Boston Healthcare System, Boston, MA, USA;
Clin Epidemiol. 2010 Aug 9;2:23-8. doi: 10.2147/clep.s9373.
Adjustment disorder is a diagnosis given following a significant psychosocial stressor from which an individual has difficulty recovering. The individual's reaction to this event must exceed what would be observed among similar people experiencing the same stressor. Adjustment disorder is associated with suicidal ideation and suicide attempt. However the association between adjustment disorder and completed suicide has yet to be examined. The current study is a population-based case control study examining this association in the population of Denmark aged 15 to 90 years. All suicides in Denmark from 1994 to 2006 were included, resulting in 9,612 cases. For each case, up to 30 controls were matched on gender, exact date of birth, and calendar time, yielding 199,306 controls. Adjustment disorder diagnosis was found in 7.6% of suicide cases and 0.52% of controls. Conditional logistic regression analyses revealed that those diagnosed with adjustment disorder had 12 times the rate of suicide as those without an adjustment disorder diagnosis, after controlling for history of depression diagnosis, marital status, income, and the matched factors.
适应障碍是在经历重大心理社会应激后出现的一种诊断,患者难以从中恢复。个体对这一事件的反应必须超过在经历同样应激源的相似人群中观察到的反应。适应障碍与自杀意念和自杀企图有关。然而,适应障碍与自杀完成之间的关联尚未得到检验。本研究是一项基于人群的病例对照研究,旨在检查丹麦 15 至 90 岁人群中的这种关联。纳入了 1994 年至 2006 年丹麦的所有自杀者,共 9612 例。对于每例病例,按性别、确切出生日期和日历时间匹配了最多 30 例对照,共 199306 例对照。在自杀病例中发现适应障碍诊断占 7.6%,而在对照组中占 0.52%。条件逻辑回归分析显示,在控制了抑郁诊断史、婚姻状况、收入和匹配因素后,被诊断为适应障碍的患者自杀率是没有适应障碍诊断的患者的 12 倍。