Goldberg Leonard H, Mamelak Adam J
DermSurgery Associates, Houston, TX, USA.
J Drugs Dermatol. 2010 Sep;9(9):1125-32.
Clinically, actinic keratoses (solar keratoses) are keratotic lesions that occur on chronically sunlight-exposed skin. Histologically, they are epidermal tumors. Presenting with a spectrum of clinical features, actinic keratoses are believed to be predictors and precursors of invasive squamous cell carcinoma. This, the first of a two-part overview, examines the etiology and epidemiology of actinic keratoses, their clinical and histological features and their role in the development of nonmelanoma skin cancer.
临床上，光化性角化病（日光性角化病）是发生在长期暴露于阳光下皮肤的角化性病变。从组织学上看，它们是表皮肿瘤。光化性角化病呈现出一系列临床特征，被认为是浸润性鳞状细胞癌的预测指标和前驱病变。这是一篇分两部分的综述中的第一篇，探讨了光化性角化病的病因学和流行病学、其临床和组织学特征以及它们在非黑素瘤皮肤癌发生过程中的作用。
