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2009年美国预防服务工作组(USPSTF)的指南没有科学依据:乳腺钼靶筛查的科学支持。

The 2009 US Preventive Services Task Force (USPSTF) guidelines are not supported by science: the scientific support for mammography screening.

作者信息

Kopans Daniel B

机构信息

Department of Radiology, Harvard Medical School, Shattuck Street, Boston, MA, USA.

出版信息

Radiol Clin North Am. 2010 Sep;48(5):843-57. doi: 10.1016/j.rcl.2010.06.005.

DOI:10.1016/j.rcl.2010.06.005
PMID:20868889
Abstract

Mammography screening is one of the major medical accomplishments of the past 40 years. In light of the downstream consequences of any screening test, it was critical that mammography screening be challenged. There have been many legitimate challenges, as well as many challenges that are not scientifically based but have gained credibility because of repetition. The latter have led to a great deal of confusion among women and their physicians. The aim of this review is to dispel many of the misunderstandings that have developed in the past 4 decades and, hopefully, reduce the confusion that has occurred. Mammography screening does not find all breast cancers and does not find all cancers early enough to result in a cure, but it is a major advance, and women should not be denied access to its benefits.

摘要

乳房X光筛查是过去40年的主要医学成就之一。鉴于任何筛查测试的下游后果,对乳房X光筛查提出质疑至关重要。存在许多合理的质疑,也有许多并非基于科学但因反复提及而获得可信度的质疑。后者在女性及其医生中造成了极大的困惑。本综述的目的是消除过去40年中产生的许多误解,并有望减少已出现的困惑。乳房X光筛查并不能发现所有乳腺癌,也不能足够早地发现所有癌症以实现治愈,但它是一项重大进展,女性不应被剥夺获得其益处的机会。

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No evidence of excessive cancer screening in female noncarriers from mutation-positive families.来自突变阳性家族的女性非携带者中无过度癌症筛查的证据。
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Breast cancer screening panels continue to confuse the facts and inject their own biases.
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