Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, NC 27710, USA.
Am J Obstet Gynecol. 2011 Jan;204(1):65.e1-6. doi: 10.1016/j.ajog.2010.08.020.
We sought to assess perioperative outcomes of minimally invasive vs open endometrial cancer staging procedures.
A total of 181 consecutive patients underwent open or minimally invasive hysterectomy with or without lymphadenectomy. Perioperative outcomes, analgesic, and antiemetic use were compared.
In all, 97 and 84 women underwent open and minimally invasive staging procedures, respectively. In the open staging group, median anesthesia time was shorter (197 vs 288 minutes; P < .0001), but recovery room stay (168 vs 140 minutes; P = .01) and hospital stay (4 vs 1 day; P < .0001) were longer. Median narcotic (13 vs 43 mg morphine equivalents; P < .0001) and antiemetic (43% vs 25%; P = .01) use were lower for minimally invasive surgery in the first 24 hours postoperatively. Median estimated blood loss was lower for minimally invasive procedures (100 vs 300 mL; P < .0001).
Minimally invasive staging for endometrial cancer is associated with lower use of narcotics and antiemetics, and shorter hospital stay compared to open procedures.
我们旨在评估微创与开放子宫内膜癌分期手术的围手术期结局。
总共 181 例连续患者接受了开放或微创子宫切除术，伴或不伴淋巴结切除术。比较了围手术期结局、镇痛和止吐药物的使用情况。
共有 97 例和 84 例女性分别接受了开放和微创分期手术。在开放分期组中，麻醉时间中位数更短（197 对 288 分钟；P<.0001），但恢复室停留时间（168 对 140 分钟；P=.01）和住院时间（4 对 1 天；P<.0001）更长。术后 24 小时内，微创手术的麻醉药物（13 对 43 毫克吗啡当量；P<.0001）和止吐药物（43%对 25%；P=.01）使用中位数较低。微创手术的估计失血量中位数较低（100 对 300 毫升；P<.0001）。
与开放手术相比，微创分期治疗子宫内膜癌与使用阿片类药物和止吐药物较少、住院时间较短相关。
