Department of Electrical Engineering and Computer Science, University of Missouri, Kansas City, MO 64112, USA.
Comput Med Imaging Graph. 2011 Jan;35(1):9-15. doi: 10.1016/j.compmedimag.2010.08.006.
Cardiac studies are a good candidate for SPECT (single photon emission computed tomography) because of the large clinical demand and the need for improved image quality. But SPECT imaging suffers from poor spatial resolution and high statistical noise. A new SPECT system with slit-slat collimation arranged on an elliptical arc for cardiac imaging is proposed in this paper. Simulated emission computed tomography data are generated along an elliptical moving orbit with system configuration parameters. The iterative reconstruction techniques are used to implement the cardiac imaging of the proposed SPECT system. Image reconstruction can be done using the OS-EM algorithm from the data collected. This system is developed to improve the reconstructed image if attenuation correction and depth-dependent correction are included in the reconstruction, and the body contour is used in the reconstruction for severely truncated data. The simulation results show that the present methods can provide significant improvement in the spatial resolution and the image quality of SPECT sets.
心脏研究是 SPECT(单光子发射计算机断层扫描)的一个很好的候选对象,因为它有大量的临床需求,并且需要提高图像质量。但是 SPECT 成像受到空间分辨率差和统计噪声高的限制。本文提出了一种新的 SPECT 系统,该系统在椭圆弧上排列狭缝准直器,用于心脏成像。利用系统配置参数,沿着椭圆形移动轨道生成模拟发射计算机断层扫描数据。迭代重建技术用于实现所提出的 SPECT 系统的心脏成像。可以从收集的数据中使用 OS-EM 算法进行图像重建。如果在重建中包括衰减校正和深度相关校正,并且在严重截断数据的重建中使用身体轮廓,则开发此系统可提高重建图像的质量。模拟结果表明,这些方法可以显著提高 SPECT 设备的空间分辨率和图像质量。