Klinik für Psychiatrie und Psychotherapie, Charité Campus Mitte, University Medicine Berlin, Germany.
J Affect Disord. 2011 Mar;129(1-3):75-8. doi: 10.1016/j.jad.2010.08.016. Epub 2010 Sep 24.
Weight increase is a problem in women with bipolar disorder (BD). Furthermore, there is evidence that both binge eating disorder (BED) and menstrual cycle abnormalities occur more frequently in women with affective disorders than in the general population. We investigated whether there is a clinical link between the two disorders and menstrual cycle.
Epidemiological and clinical variables associated with both BD and BED were assessed as well as menstrual cycle influence.
The prevalence of BED in the sample was 28.8%. Menstrual cycle significantly influenced BED in all participants in that BED became worse prior to menses. 80% of the participants noticed regular weight gain prior to menses.
BED is a common comorbidity in unmedicated subjects with BD, as is overweight. In women with BD menstrual cycle should be taken into consideration, as it can worsen the BD itself and associated comorbidities such as BED and overweight. Alteration in menstrual cycle-associated eating behavior should be routinely assessed in women with BD.
体重增加是双相情感障碍（BD）女性的一个问题。此外，有证据表明，与普通人群相比，情感障碍女性中暴食障碍（BED）和月经周期异常更为常见。我们调查了这两种疾病与月经周期之间是否存在临床联系。
评估了与 BD 和 BED 相关的流行病学和临床变量，以及月经周期的影响。
该样本中 BED 的患病率为 28.8%。月经周期对所有参与者的 BED 都有显著影响，即在月经前 BED 会恶化。80%的参与者注意到在月经前体重会有规律地增加。
在未经药物治疗的 BD 患者中，BED 是一种常见的共病，超重也是如此。在 BD 女性中应考虑月经周期，因为它会使 BD 本身以及相关的共病（如 BED 和超重）恶化。应定期评估 BD 女性与月经周期相关的饮食行为改变。
