Department of Diabetes Research, University Hospitals of Leicester NHS Trust, Leicester, UK.
Prim Care Diabetes. 2011 Apr;5(1):45-56. doi: 10.1016/j.pcd.2010.08.002. Epub 2010 Sep 25.
Type 2 diabetes (T2DM) is growing at a pandemic scale and is associated with a rapid increase in its complications such as cardiovascular diseases (CVD). This problem is even worse in South Asian population with South Asian people having a much higher prevalence of T2DM and CVD, occurring at an earlier age and being associated with premature and high mortality. This review looks in detail at the current knowledge on epidemiology and characteristic pathophysiology of T2DM and CVD (coronary heart disease, heart failure, stroke and peripheral vascular disease) in South Asian migrant population. Specific attention is also drawn to the role of novel risk factors and cultural and socioeconomic factors on occurrence and outcomes of these chronic diseases in this population. Finally the review makes recommendations on various measures including need for further research to tackle this serious health challenge facing the South Asian community.
2 型糖尿病(T2DM)正在以流行病的规模增长,并与心血管疾病(CVD)等并发症的迅速增加有关。南亚人群的这个问题更为严重,南亚人群的 T2DM 和 CVD 患病率更高,发病年龄更早,与过早和高死亡率相关。这篇综述详细探讨了南亚移民人群中 T2DM 和 CVD(冠心病、心力衰竭、中风和外周血管疾病)的流行病学和特征性病理生理学的现有知识。还特别关注了新型危险因素以及文化和社会经济因素对这些慢性病在该人群中发生和结局的影响。最后,该综述就各种措施提出了建议,包括需要进一步研究来应对南亚社区面临的这一严重健康挑战。