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炎症性肠病患者 LASIK 术后手术诱导性角膜坏死性角膜炎

Surgically induced corneal necrotizing keratitis following LASIK in a patient with inflammatory bowel disease.

机构信息

London Vision Clinic, London, United Kingdom.

出版信息

J Cataract Refract Surg. 2010 Oct;36(10):1786-9. doi: 10.1016/j.jcrs.2010.06.046.

Abstract

We describe a case of necrotizing keratitis that developed after laser in situ keratomileusis (LASIK) in a 50-year-old woman with inflammatory bowel disease. The patient had not disclosed her history of a total colectomy for recurrent ulcerative colitis and developed bilateral stromal inflammation and corneal melting along the flap edge with ulceration within 3 days of uneventful bilateral LASIK for myopia. She was aggressively managed with topical and systemic corticosteroid therapy. Flap infiltrates gradually resolved, with no relapse during the 12-month follow-up. This case highlights the importance of taking a detailed history, specifically addressing autoimmune diseases, before corneal refractive surgery.

摘要

我们描述了一例 50 岁女性发生的 LASIK 术后坏死性角膜炎,该患者患有炎症性肠病。患者未透露她因复发性溃疡性结肠炎而接受全结肠切除术的病史,在双眼无并发症 LASIK 治疗近视后 3 天,出现双侧基质炎症和沿瓣缘角膜融解伴溃疡。她接受了积极的局部和全身皮质类固醇治疗。瓣下浸润逐渐消退,在 12 个月的随访中无复发。该病例强调了在进行角膜屈光手术前详细询问病史,特别是询问自身免疫性疾病的重要性。

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