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经内镜导丝定位或美蓝注射引导下选择性微切开术治疗乳腺导管内原位癌的随机对照研究

A randomized controlled study of selective microdochectomy guided by ductoscopic wire marking or methylene blue injection.

机构信息

Department of General Surgery, The Second Affiliated Hospital of Soochow University, Jiangsu, People's Republic of China.

出版信息

Am J Surg. 2011 Feb;201(2):221-5. doi: 10.1016/j.amjsurg.2010.03.011. Epub 2010 Sep 26.

DOI:10.1016/j.amjsurg.2010.03.011
PMID:20870205
Abstract

BACKGROUND

Methylene blue identification of lesions during microdochectomy is often inaccurate, resulting in large dissection and tissue damage. A wire placed via ductoscopy preoperatively into the pathologic duct may aid identification and reduce the amount of dissection required.

METHODS

A total of 53 patients being evaluated for nipple discharge were randomized to receive ductoscopy with either methylene blue or wire marking of the lesion before microdochectomy. Patient clinical characteristics and surgical outcomes were evaluated.

RESULTS

There were 28 patients who received methylene blue marking and 25 who received wire marking of the lesions. There were no differences between the demographic or clinical characteristics of the groups. Wire marking was associated with less surgical time, smaller incisions, and smaller surgical specimens, but the same diagnostic accuracy.

CONCLUSIONS

Wire marking of lesions for microdochectomy is associated with less dissection and tissue damage than methylene blue, yet the same diagnostic accuracy.

摘要

背景

在微创切除术中,亚甲蓝识别病变往往不准确,导致大量解剖和组织损伤。术前通过乳管镜将一根导丝放入病变的乳管中,可能有助于识别病变并减少所需的解剖量。

方法

共有 53 例因乳头溢液就诊的患者被随机分为两组,分别在微创切除术前接受亚甲蓝或导丝标记病变。评估患者的临床特征和手术结果。

结果

有 28 例患者接受了亚甲蓝标记,25 例患者接受了导丝标记。两组患者的人口统计学和临床特征无差异。导丝标记与手术时间更短、切口更小、手术标本更小有关,但诊断准确性相同。

结论

与亚甲蓝相比,微创切除术中导丝标记病变与更少的解剖和组织损伤相关,但诊断准确性相同。

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