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新生儿肝病社区诊治方案的审核。

An audit of a community protocol for identifying neonatal liver disease.

机构信息

Children's Liver and GI Unit, Leeds Teaching Hospitals NHS Trust, Paediatric Offices, Ward 39, Old Wing, Leeds General Infirmary, Great George Street, Leeds LS1 3EX, UK.

出版信息

Arch Dis Child. 2012 Feb;97(2):166-8. doi: 10.1136/adc.2009.179812. Epub 2010 Sep 23.

Abstract

Performing a split bilirubin test to identify liver disease in any infant who remains jaundiced beyond 2 weeks of age has been recognised as good clinical practice. The Leeds Community Midwifery Team performed this test, following an agreed protocol, from December 2000. By February 2008, 882 infants had been tested. Three infants were identified as having significant liver disease, including one with biliary atresia. Examining the liver unit database, a further 38 infants with Leeds post codes presented with neonatal liver disease during the study period. Five infants were identified appropriately by the midwives but not reported via the study protocol, 29 were referred from secondary care, (1) by a general practitioner at 9 days of age and (2) who did not become jaundiced before 3 months, leaving one infant who was 'missed' by the midwives. No infant whose conjugated bilirubin was below the authors' threshold later presented with liver disease. This is an effective protocol for identifying neonatal liver disease but requires ongoing education to maintain compliance.

摘要

对超过 2 周龄仍持续黄疸的任何婴儿进行胆红素分离检测以识别肝病,这已被认为是良好的临床实践。利兹社区助产士团队按照既定方案,从 2000 年 12 月开始执行该检测。到 2008 年 2 月,已有 882 名婴儿接受了检测。其中 3 名婴儿被确定患有明显的肝脏疾病,包括 1 名患有胆道闭锁。检查肝脏科室数据库,在研究期间,还有 38 名利兹邮编的婴儿患有新生儿肝病。有 5 名婴儿被助产士适当识别,但未通过研究方案报告,其中 29 名由二级保健机构转介,(1)由全科医生在 9 天龄时转介,(2)在 3 个月前未出现黄疸,只有 1 名婴儿被助产士“遗漏”。没有胆红素结合物低于作者阈值的婴儿后来出现肝脏疾病。这是一种识别新生儿肝病的有效方案,但需要持续教育以保持合规性。

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