Blomberg M, Blomberg Jensen M, Henry A, Singh S T, Banipal R P Singh, da Cunha-Bang C, Bygbjerg I C
Department of Viruses, Hormones and Cancer, Institute of Cancer Epidemiology, Danish Cancer Society.
Trop Doct. 2010 Oct;40(4):194-8. doi: 10.1258/td.2010.090157.
Antimicrobial drug use and overuse have been a topic of interest for many years, lately focusing on the growing resistance worldwide. This study was conducted in a small Indian hospital, where more than 80% of all admitted patients received antimicrobial drugs. Penicillin, gentamycin, co-trimoxazole, ciprofloxacin and metronidazole were most commonly used and all antimicrobial drugs were given empirically with no confirmation of the infective agent. Reports of increasing resistance to antimicrobial drugs in India, and elsewhere, necessitates a focus on how antimicrobials drugs are used in relation to investigations of resistance patterns among the local strains of pathogens. This study may be considered a base-line study, though of relevance for other hospitals, in particular in low-income areas, where development of resistance to standard antimicrobial drugs may have severe implications for both patients and health managers.
抗菌药物的使用和过度使用多年来一直是人们关注的话题，最近则聚焦于全球范围内日益增长的耐药性。这项研究是在一家小型印度医院进行的，所有入院患者中有超过80%接受了抗菌药物治疗。青霉素、庆大霉素、复方新诺明、环丙沙星和甲硝唑是最常用的药物，所有抗菌药物都是凭经验给药，并未确认感染病原体。印度及其他地区对抗菌药物耐药性增加的报告，使得有必要关注抗菌药物的使用方式与当地病原体菌株耐药模式调查之间的关系。尽管这项研究对其他医院，特别是低收入地区的医院具有相关性，因为对标准抗菌药物产生耐药性可能对患者和卫生管理人员都有严重影响，但它仍可被视为一项基线研究。
