Macura A B, Sysło J
Instytut Mikrobiologii AM w Krakowie.
Med Dosw Mikrobiol. 1990;42(1-2):84-8.
The aim of this study was to evaluate hydrophobicity of fungal strains of Candida sp. isolated from clinical materials of patients with fungal infections. Two hundred and eighty one strains of C. albicans and 29 strains belonging to the other species of Candida were tested in salt aggregation test (SAT). Strong hydrophobicity (autoaggregation in the test) was found in 29.4% of tested strains. The majority of them was isolated from vagina. In 20 randomly selected strains hydrophobicity was measured not only by salt aggregation test but also by hydrophobic interaction chromatography (MIC). The ability to attach to buccal epithelial cells in vitro was compared between 50 strongly hydrophobic strains and 30 with low hydrophobicity. The former strains attached significantly stronger (p less than 0.001).
本研究的目的是评估从真菌感染患者临床材料中分离出的念珠菌属真菌菌株的疏水性。对281株白色念珠菌菌株和29株属于其他念珠菌属的菌株进行了盐聚集试验（SAT）。在29.4%的受试菌株中发现了强疏水性（试验中的自聚集）。其中大多数菌株是从阴道分离出来的。在20株随机选择的菌株中，不仅通过盐聚集试验，还通过疏水相互作用色谱法（MIC）测量了疏水性。比较了50株强疏水性菌株和30株低疏水性菌株在体外与颊上皮细胞的附着能力。前一组菌株的附着能力明显更强（p小于0.001）。
