Davenport Laboratory, Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, Ontario M5S 3H6, Canada.
Chem Commun (Camb). 2010 Nov 21;46(43):8240-2. doi: 10.1039/c0cc02664f. Epub 2010 Sep 27.
The complex [RuCp*(C-NH(2))(py)]PF(6) bearing a chelating N-heterocyclic carbene with an NH(2) group (C-NH(2)) is an active catalyst for the H(2)-hydrogenation of ketones, an epoxide, ester and ketimine in basic solution. A maximum turnover frequency of 17,600 h(-1) is achieved under mild reaction conditions (25 °C) and economical use of hydrogen (8 bar) while the TOF of a related complex with a phosphine-amine ligand is much smaller.
该配合物[RuCp*(C-NH(2))(py)]PF(6)中的配体为含有一个 NH(2)基团（C-NH(2))的螯合 N-杂环卡宾，它是酮、环氧化物、酯和酮亚胺在碱性溶液中氢化反应的高效催化剂。在温和的反应条件（25°C）和经济氢气压力（8 巴）下，该配合物可实现高达 17600 h(-1)的最大周转频率，而具有膦-胺配体的相关配合物的 TOF 要小得多。
