Department of Chest Surgery, Medical School of Dicle University, Diyarbakir, Turkey.
Biol Trace Elem Res. 2011 Oct;143(1):359-67. doi: 10.1007/s12011-010-8855-2. Epub 2010 Sep 25.
Electromagnetic field (EMF) can affect cells due to biochemical change followed by a change in level of ions trafficking through membrane. We aimed to investigate possible changes in some elements in costa of rats exposed to long-term extremely low-frequency magnetic field (ELF-MF). Rats were exposed to 100 and 500 μT ELF-MF, which are the safety standards of public and occupational exposure for 2 h/day during 10 months. At the end of the exposure period, the samples of costa were taken from the rats exposed to ELF-MF and sham. The levels of elements were measured by using atomic absorption spectrophotometry (AAS) and ultraviolet (UV) spectrophotometry. Ca levels decreased in the ELF-500 exposure group in comparison to sham group (p < 0.05). Statistically significant decrease was found in Mg levels in the ELF-500 exposure group in comparison to sham and ELF-100 exposure groups (p < 0.05). Zn levels were found to be lower in the ELF-500 exposure group than those in the sham and ELF-100 exposure groups (p < 0.05). No significant differences were determined between groups in terms of the levels of P, Cu and Fe. In conclusion, it can be maintained that long-term ELF-MF exposure can affect the chemical structure and metabolism of bone by changing the levels of some important elements such as Ca, Zn and Mg in rats.
电磁场（EMF）可以通过改变离子穿过细胞膜的水平来影响细胞，这是由于生化变化引起的。我们旨在研究长期暴露于极低频磁场（ELF-MF）下的大鼠桡骨中某些元素可能发生的变化。大鼠每天暴露于 100 和 500 μT 的 ELF-MF 中 2 小时，这是公众和职业暴露的安全标准，持续 10 个月。在暴露期结束时，从暴露于 ELF-MF 和假暴露的大鼠中取出桡骨样本。使用原子吸收分光光度法（AAS）和紫外（UV）分光光度法测量元素水平。与假暴露组相比，ELF-500 暴露组的 Ca 水平降低（p < 0.05）。与假暴露组和 ELF-100 暴露组相比，ELF-500 暴露组的 Mg 水平显著降低（p < 0.05）。与假暴露组和 ELF-100 暴露组相比，ELF-500 暴露组的 Zn 水平较低（p < 0.05）。各组之间的 P、Cu 和 Fe 水平没有差异。总之，可以认为长期 ELF-MF 暴露可以通过改变 Ca、Zn 和 Mg 等一些重要元素的水平来影响大鼠的骨骼化学结构和代谢。
