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[与妊娠相关的肝脏疾病的发病机制]

[Pathogenesis of liver diseases associated with pregnancy].

作者信息

Cichoz-Lach Halina

机构信息

Katedra i Klinika Gastroenterologii UM w Lublinie.

出版信息

Ginekol Pol. 2010 Aug;81(8):613-7.

Abstract

Liver diseases in pregnancy constitute substantial clinical problem. Liver diseases occurring only during pregnancy, include: intrahepatic cholestasis of pregnancy acute fatty liver of pregnancy HELLP syndrome, pre-eclampsia and eclampsia. They can be associated with significant maternal and fetal morbidity and mortality The following article explores the pathogenesis, the clinical features, risk factors and management of above listed disorders. Early diagnosis and immediate decisions are essential for maternal and fetal survival.

摘要

妊娠期间的肝脏疾病构成了重大的临床问题。仅在妊娠期间发生的肝脏疾病包括:妊娠肝内胆汁淤积症、妊娠急性脂肪肝、HELLP综合征、先兆子痫和子痫。它们可能伴有严重的母婴发病和死亡情况。以下文章探讨了上述疾病的发病机制、临床特征、危险因素及管理方法。早期诊断和及时决策对母婴存活至关重要。

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