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[发育中神经元网络的自发活动]

[Spontaneous activity of the developing neuronal networks].

作者信息

Sheroziia M G, Egorov A V

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 2010 Jul-Aug;60(4):387-96.

PMID:20873128
Abstract

A review. Spontaneous periodic network activity is a characteristic feature of the developing nervous system. It is believed that early spontaneous activity is involved in the modulation of several processes during brain maturation, including neuronal growth and network construction. Periodic spontaneous network activity was observed and studied in detail in hippocampus, cortex, retina and spinal cord of embryos and newborn animals. Principal studies of spontaneous network activity in the developing nervous system are reviewed, and possible mechanisms of its generation are discussed.

摘要

综述。自发周期性网络活动是发育中神经系统的一个特征。人们认为早期的自发活动参与了大脑成熟过程中多个进程的调节,包括神经元生长和网络构建。在胚胎和新生动物的海马体、皮层、视网膜和脊髓中观察并详细研究了周期性自发网络活动。本文综述了发育中神经系统自发网络活动的主要研究,并讨论了其产生的可能机制。

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