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紧张性头痛的发病机制。

Stress and tension-type headache mechanisms.

机构信息

Centre for Applied Psychological Research, School of Psychology, University of South Australia, Adelaide, Australia.

出版信息

Cephalalgia. 2010 Oct;30(10):1250-67. doi: 10.1177/0333102410362927.

DOI:10.1177/0333102410362927
PMID:20873360
Abstract

Stress is widely demonstrated as a contributing factor in tension-type headache (TTH). The mechanisms underlying this remain unclear at present. Recent research indicates the importance of central pain processes in tension-type headache (TTH) pathophysiology. Concurrently, research with animals and healthy humans has begun to elucidate the relationship between stress and pain processing in the central nervous system, including central pain processes putatively dysfunctional in TTH. Combined, these two fields of research present new insights and hypotheses into possible mechanisms by which stress may contribute to TTH. To date, however, there has been no comprehensive review of this literature. The present paper provides such a review, which may be valuable in facilitating a broader understanding of the central mechanisms by which stress may contribute to TTH.

摘要

压力被广泛认为是紧张型头痛(TTH)的一个致病因素。目前,其潜在机制尚不清楚。最近的研究表明中枢疼痛过程在紧张型头痛(TTH)病理生理学中的重要性。同时,对动物和健康人类的研究已经开始阐明中枢神经系统中压力与疼痛处理之间的关系,包括 TTH 中可能功能失调的中枢疼痛过程。这两个研究领域结合起来,为压力可能导致 TTH 的可能机制提供了新的见解和假设。然而,迄今为止,尚未对此文献进行全面综述。本文提供了这样的综述,这可能有助于更广泛地理解压力可能导致 TTH 的中枢机制。

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