Beloborodova E I, Chelnova I P, Beloborodova E V, Chelnov V G, Tiukalova L I, Purlik I L, Chvyrina D V, Shkorlupa S G
Med Parazitol (Mosk). 2010 Jul-Sep(3):16-20.
The aim of the investigation was to study the myocardium in patients with chronic viral hepatitis concurrent with chronic opisthorchiasis. Ninety patients with chronic viral hepatitis, including 52 patients with this disease concurrent with chronic opisthorchiasis, were examined. Doppler echocardiography indicated a statistically significant increase in left ventricular mass regardless of the presence of Opisthorchis infestation. Analysis of left ventricular diastolic dysfunction showed its great degree in chronic hepatitis C. Single-photon emission computed tomography with 99mTc-pyrophosphate revealed focal tracer incorporation in the myocardium of most patients with Opisthorchis infestation. A third of patients with chronic viral hepatitis showed moderate diffuse trace accumulation that was significantly more frequently found in chronic hepatitis C. Single photon-emission tomography with labeled leukocytes demonstrated abnormal accumulation in none of the patients; troponin T levels were in the normal allowable range. Myocardial lesion was detected in the chronic course of viral hepatitis C concurrent with chronic opisthorchiasis that was unattended by cardiomyocyte necrosis and that was dystrophic.
该研究的目的是对合并慢性后睾吸虫病的慢性病毒性肝炎患者的心肌进行研究。对90例慢性病毒性肝炎患者进行了检查，其中52例合并慢性后睾吸虫病。多普勒超声心动图显示，无论是否存在后睾吸虫感染，左心室质量均有统计学意义的增加。对左心室舒张功能障碍的分析表明，其在慢性丙型肝炎中程度较重。用99mTc-焦磷酸盐进行的单光子发射计算机断层扫描显示，大多数后睾吸虫感染患者的心肌中有局灶性示踪剂摄取。三分之一的慢性病毒性肝炎患者显示出中度弥漫性示踪剂积聚，在慢性丙型肝炎中更为常见。标记白细胞的单光子发射断层扫描显示所有患者均无异常积聚；肌钙蛋白T水平在正常允许范围内。在合并慢性后睾吸虫病的慢性丙型病毒性肝炎病程中检测到心肌病变，该病变无心肌细胞坏死，属于营养不良性病变。
