Kalfas S, Edwardsson S
School of Dentistry, University of Lund, Malmo, Sweden.
Oral Microbiol Immunol. 1990 Feb;5(1):33-8. doi: 10.1111/j.1399-302x.1990.tb00223.x.
The sorbitol-fermenting predominant flora of human dental plaque was studied in 12 people with low and 11 with normal salivary secretion rates before and after a period of frequent mouth rinses with sorbitol solution. A total of 277 sorbitol-fermenting isolates are described by their morphological and physiological characteristics. The flora was almost exclusively composed of gram-positive bacteria belonging to the genera Streptococcus, Lactobacillus and Actinomyces in people with low secretion rates and Streptococcus and Actinomyces in those with normal salivation. At the species level, Streptococcus mutans predominated in all. The frequent use of sorbitol resulted in an increase of the streptococcal species mainly and particularly of Streptococcus sanguis I in people with normal salivation. The counts of lactobacilli and Actinomyces remained unaffected. Almost all isolates appeared to belong to the resident plaque flora. Succession of new sorbitol-fermenting genera to the plaque community could not be observed as a result of the frequent exposure of the mouth to sorbitol.
在12名唾液分泌率低的人和11名唾液分泌率正常的人身上，研究了在使用山梨醇溶液频繁漱口一段时间前后，人牙菌斑中发酵山梨醇的主要菌群。根据形态和生理特征描述了总共277株发酵山梨醇的分离菌。在唾液分泌率低的人中，该菌群几乎完全由革兰氏阳性菌组成，属于链球菌属、乳杆菌属和放线菌属；在唾液分泌正常的人中，该菌群由链球菌属和放线菌属组成。在种的水平上，变形链球菌在所有人中占主导地位。频繁使用山梨醇主要导致链球菌种类增加，尤其是在唾液分泌正常的人中血链球菌I增加。乳杆菌和放线菌的数量未受影响。几乎所有分离菌似乎都属于牙菌斑常驻菌群。由于口腔频繁接触山梨醇，未观察到新的发酵山梨醇菌属在牙菌斑群落中的演替。
