Aspromonte Nadia, Di Tano Giuseppe, Latini Roberto, Masson Serge, Valle Roberto, Emdin Michele
Dipartimento Cardiovascolare, Ospedale San Filippo Neri, Roma.
G Ital Cardiol (Rome). 2010 May;11(5 Suppl 2):17S-23S.
Recent advances in the understanding of the pathophysiology of heart failure have made available among novel diagnostic tools an increasing number of biohumoral markers. In the setting of chronic heart failure, natriuretic peptides and troponins have been proposed for routine clinical use to evaluate functional severity of cardiac damage, for prognostic stratification across the whole spectrum of disease evolution, to assess treatment effectiveness, and to guide therapy. We discuss their clinical significance and role in a tailored strategy for patient follow-up.
近年来，在心力衰竭病理生理学认识方面取得的进展使得越来越多的生物体液标志物成为新型诊断工具。在慢性心力衰竭的情况下，利钠肽和肌钙蛋白已被建议用于常规临床应用，以评估心脏损伤的功能严重程度，对疾病发展全过程进行预后分层，评估治疗效果，并指导治疗。我们讨论了它们在针对患者随访的定制策略中的临床意义和作用。
