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[Memory and intellectual disorders in patients with epilepsy: an analysis of the relationship between clinical characteristics and brain asymmetry].

作者信息

Nazmetdinova D M, Basamygin A V, Kalinin V V

出版信息

Zh Nevrol Psikhiatr Im S S Korsakova. 2010;110(3 Suppl 2):82-7.

PMID:20873480
Abstract

Clinical characteristics and cognitive functions have been studied during the examination and treatment of 132 patients with epilepsy. It has been shown that both the epileptic process by itself and the antiepileptic therapy are predictors of the memory-intellectual impairment. The key risk factors of cognitive impairment are the younger age of patients at the onset of seizures, the higher frequency of seizures and the secondary generalization. We found the effect of left-sided motor asymmetry on the intellectual impairment that was more pronounced in men. The left-sided profile of brain asymmetry is an unfavorable prognostic factor of the disease development.

摘要

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