Queensland Tuberculosis Control Centre, Brisbane, Queensland, Australia.
Emerg Infect Dis. 2010 Oct;16(10):1576-83. doi: 10.3201/eid1610.091201.
Nontuberculous mycobacteria (NTM) disease is a notifiable condition in Queensland, Australia. Mycobacterial isolates that require species identification are forwarded to the Queensland Mycobacterial Reference Laboratory, providing a central opportunity to capture statewide data on the epidemiology of NTM disease. We compared isolates obtained in 1999 and 2005 and used data from the Queensland notification scheme to report the clinical relevance of these isolates. The incidence of notified cases of clinically significant pulmonary disease rose from 2.2 (1999) to 3.2 (2005) per 100,000 population. The pattern of disease has changed from predominantly cavitary disease in middle-aged men who smoke to fibronodular disease in elderly women. Mycobacterium intracellulare is the main pathogen associated with the increase in isolates speciated in Queensland.
非结核分枝杆菌（NTM）疾病在澳大利亚昆士兰州是一种须报告的疾病。需要进行菌种鉴定的分枝杆菌分离株会被转送至昆士兰分枝杆菌参考实验室，这为全州范围内捕获 NTM 疾病的流行病学数据提供了一个中心机会。我们比较了 1999 年和 2005 年获得的分离株，并使用昆士兰州报告计划的数据来报告这些分离株的临床相关性。临床显著的肺部疾病的报告发病率从每 100,000 人口 2.2 例（1999 年）上升至 3.2 例（2005 年）。疾病模式已从以吸烟的中年男性为主的空洞性疾病转变为老年女性的纤维结节性疾病。与在昆士兰州鉴定的分离株数量增加相关的主要病原体是胞内分枝杆菌。
