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剖宫产术与术后粘连和肠梗阻的风险:一项基于瑞典医疗出生登记的巢式病例对照研究。

Cesarean delivery and risk for postoperative adhesions and intestinal obstruction: a nested case-control study of the Swedish Medical Birth Registry.

机构信息

Division of Obstetrics and Gynecology, Department of Clinical Sciences, Karolinska Institutet, Danderyd Hospital, Stockholm, Sweden.

出版信息

Am J Obstet Gynecol. 2010 Oct;203(4):406.e1-6. doi: 10.1016/j.ajog.2010.07.013.

Abstract

OBJECTIVE

The objective of the study was to estimate the risk for postoperative adhesions and intestinal obstruction after cesarean delivery and to estimate whether the rate remains stable over time.

STUDY DESIGN

Women who had the aforementioned diagnoses in the Swedish Hospital Discharge Registry were linked to the Swedish Medical Birth Registry. Women with diagnoses increasing the risk for adhesions were excluded. More than 900,000 women were investigated. Risks were calculated and were adjusted for age, parity, body mass index, and smoking.

RESULTS

Women delivered by cesarean delivery had an increased risk of adhesions: adjusted odds ratio, 2.1 (95% confidence interval, 1.8-2.4) and intestinal obstruction: adjusted odds ratio, 2.0 (95% confidence interval, 1.7-2.4). The number needed to harm was 360. Multiple caesarean deliveries increased the risk of adhesions. The risk did not increase over time.

CONCLUSION

The absolute risk of postoperative adhesions and intestinal obstruction after cesarean section are low but should be included when counseling women requesting cesarean delivery.

摘要

目的

本研究旨在评估剖宫产术后粘连和肠梗阻的风险,并估计该风险是否随时间保持稳定。

研究设计

将瑞典住院患者出院登记系统中出现上述诊断的女性与瑞典医疗出生登记系统相关联。排除有增加粘连风险的诊断的女性。对超过 90 万名女性进行了调查。计算了风险,并根据年龄、产次、体重指数和吸烟状况进行了调整。

结果

剖宫产分娩的女性发生粘连的风险增加:调整后的优势比为 2.1(95%置信区间,1.8-2.4),肠梗阻的风险增加:调整后的优势比为 2.0(95%置信区间,1.7-2.4)。需要伤害的人数为 360 人。多次剖宫产会增加粘连的风险。风险并未随时间增加。

结论

剖宫产术后粘连和肠梗阻的绝对风险较低,但在为要求剖宫产的女性提供咨询时应将其纳入考虑。

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