剖宫产与盆腔器官脱垂风险：一项巢式病例对照研究。
Cesarean section and risk of pelvic organ prolapse: a nested case-control study.
作者信息
Larsson Christina, Källen Karin, Andolf Ellika
机构信息
Division of Obstetrics and Gynecology, Department of Clinical Sciences, Karolinska Institutet, Danderyd Hospital, Stockholm, Sweden.
出版信息
Am J Obstet Gynecol. 2009 Mar;200(3):243.e1-4. doi: 10.1016/j.ajog.2008.11.028.
OBJECTIVE
The objective of the study was to investigate the association between cesarean section and pelvic organ prolapse.
STUDY DESIGN
The Swedish Hospital Discharge Registry was used to identify women with an inpatient diagnosis of pelvic organ prolapse, and the data were linked to the Swedish Medical Birth Registry. Odds ratios (ORs) were estimated using the Mantel-Haenzsel procedure and Cox analyses to estimate hazard ratios. The material was stratified for age and parity.
RESULTS
A total of 1.4 million women were investigated. A strong and statistically significant association between cesarean section and pelvic organ prolapse was found. Adjusted OR was 0.18 (0.16-0.20) and overall hazard ratio 0.20 (0.18-0.22).
CONCLUSION
Cesarean section is associated with a lower risk of pelvic organ prolapse than vaginal delivery.
目的
本研究的目的是调查剖宫产与盆腔器官脱垂之间的关联。
研究设计
利用瑞典医院出院登记系统识别出住院诊断为盆腔器官脱垂的女性，并将数据与瑞典医学出生登记系统相链接。采用Mantel-Haenzsel法估计比值比（OR），并通过Cox分析估计风险比。资料按年龄和产次进行分层。
结果
共调查了140万名女性。发现剖宫产与盆腔器官脱垂之间存在强烈且具有统计学意义的关联。校正后的OR为0.18（0.16 - 0.20），总体风险比为0.20（0.18 - 0.22）。
结论
与阴道分娩相比，剖宫产与盆腔器官脱垂风险较低相关。
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