The evolving methodology to perform limb lymphoscintigraphy: from rest to exercise acquisition protocol.

In this technical report, prepared following the kind invitation of Professor D'Amore, we describe the evolution in the methodology of performing the limb lymphoscintigraphy. In details we described and compared the rest protocol with subcutaneous injection of the radio-colloids vs. the exercise intradermal injection protocol. The latter appears to be faster and easier to interpret, moreover allowing an adequate measurements of quantitative parameters of lymph drainage and distribution.