Weissleder H, Weissleder R
Department of Radiology, Kreiskrankenhaus Emmendingen, Federal Republic of Germany.
Radiology. 1988 Jun;167(3):729-35. doi: 10.1148/radiology.167.3.3363131.
Lymphoscintigraphy was performed in 128 patients with primary lymphedema, in 91 patients with secondary lymphedema, and in 19 healthy volunteers. A total of 457 extremities were examined. Technetium-99m-labeled human serum albumin was injected subcutaneously, and passive muscular exercise was standardized to reduce the variability of lymphatic function. The scintigrams were analyzed for visualization of lymph vessels and lymph nodes, dilatation of lymphatic vessels, existence of collateral vessels, and dermal backflow. With this qualitative interpretation alone, the diagnosis of lymphedema was established in 216 of 308 extremities (70.1%). Quantitative parameters derived from clearance data showed abnormal lymphatic function in all 308 extremities. Whereas qualitative lymphoscintigraphy allows the characterization of lymphatic morphology, quantitative lymphoscintigraphy is very accurate in detection of incipient lymphedema.
对128例原发性淋巴水肿患者、91例继发性淋巴水肿患者和19名健康志愿者进行了淋巴闪烁造影检查。共检查了457个肢体。将99m锝标记的人血清白蛋白皮下注射，并对被动肌肉运动进行标准化以减少淋巴功能的变异性。对闪烁图进行分析，以观察淋巴管和淋巴结的显影、淋巴管的扩张、侧支血管的存在以及皮肤逆流情况。仅通过这种定性解释，在308个肢体中的216个（70.1%）确诊为淋巴水肿。从清除数据得出的定量参数显示，所有308个肢体的淋巴功能均异常。定性淋巴闪烁造影可对淋巴形态进行特征描述，而定量淋巴闪烁造影在检测早期淋巴水肿方面非常准确。
