Cano F, Rodríguez E, Delucchi M A, Wolff E
Unidad de Nefrología y Hemodiálisis, Hospital Luis Calvo Mackenna.
Rev Chil Pediatr. 1990 Jul-Aug;61(4):202-5.
In 50 children with hematuria or urolithiasis and idiopathic hypercalciuria, and in 15 control children, urinary calcium/creatinine concentration rates were measured after fasting and after calcium loading. Patients were classified into two groups depending on the results of an orally administered calcium loading test. Children were considered to have absorptive hypercalciuria (42%) when they had low fasting urinary calcium/creatinine concentration ratio (less than 0.21), and a large increase of this index after calcium administration (greater than 0.28). Patients were labeled as renal hypercalciuria (32%) if they had high fasting urinary calcium/creatinine concentration ratio (greater than 0.21), and variable increases of it after calcium overload. A third group of children (26%), were not classifiable by means of this test. Our data support the contention that this simple ambulatory test is very useful in the diagnostic workup of idiopathic hypercalciuria.
对50例血尿或尿路结石且患有特发性高钙尿症的儿童以及15例对照儿童,在禁食后和钙负荷后测量尿钙/肌酐浓度率。根据口服钙负荷试验的结果将患者分为两组。当儿童禁食时尿钙/肌酐浓度比低(小于0.21)且补钙后该指标大幅升高(大于0.28)时,被认为患有吸收性高钙尿症(42%)。如果患者禁食时尿钙/肌酐浓度比高(大于0.21)且钙负荷后该指标变化不定,则被标记为肾性高钙尿症(32%)。第三组儿童(26%)无法通过该试验分类。我们的数据支持以下观点,即这种简单的门诊试验在特发性高钙尿症的诊断检查中非常有用。