Garbis J M, Robert E, Peters P W
Department of Teratology, National Institute of Public Health and Environmental Protection, Bilthoven, The Netherlands.
Teratology. 1990 Dec;42(6):629-34. doi: 10.1002/tera.1420420607.
Teratology Information Services (TIS) are started in different countries in Europe in order to gather available data on exogenous agents, to evaluate their pertinence to human subjects, and to apply this knowledge to specific cases. Most European centers can only be consulted by medical professionals. The experience of two such services (Lyon, France, and Bilthoven, The Netherlands) is described. Attention is given to the task of TIS, risk evaluation, operational methods, and functioning and future developments.
为了收集有关外源性因素的现有数据、评估其与人类受试者的相关性并将这些知识应用于具体案例，欧洲不同国家纷纷启动了致畸学信息服务（TIS）。大多数欧洲中心仅接受医学专业人员的咨询。本文描述了两个此类服务机构（法国里昂和荷兰比尔特霍芬）的经验。文中关注了致畸学信息服务的任务、风险评估、操作方法、运作情况以及未来发展。
