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[舌痛症发病机制的神经源性方面]

[The neurogenic aspects of the pathogenesis of glossalgia].

作者信息

Dychko E N, Mirtovskaia V N

出版信息

Stomatologiia (Mosk). 1990 Nov-Dec;69(6):38-9.

PMID:2087716
Abstract

Comprehensive clinical, biochemical, and electrophysiologic examinations of 250 glossalgia patients have revealed disintegration of supra-segmentary vegetative formations: increased activity of sympathoadrenal and serotonin systems, depressed kallikrein-kinin system, changed level of salivary electrolytes, reduced blood supply to the facial and oral tissues and decreased sensitivity of these tissues. Based on these findings, the authors suggest a scheme of glossalgia pathogenesis, with disorders in the autonomic nervous system underlying the development of the condition. Correction of the detected shifts contributes to a more effective therapy of glossalgia.

摘要

对250例舌痛患者进行的全面临床、生化和电生理检查显示,高级神经植物性结构解体:交感肾上腺和5-羟色胺系统活性增强,激肽释放酶-激肽系统受抑制,唾液电解质水平改变,面部和口腔组织血液供应减少,这些组织的敏感性降低。基于这些发现,作者提出了舌痛发病机制的方案,自主神经系统紊乱是该病发生发展的基础。纠正所检测到的变化有助于更有效地治疗舌痛。

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