Watthanakulpanich Dorn, Waikagul Jitra, Maipanich Wanna, Nuamtanong Supaporn, Sanguankiat Surapol, Pubampen Somchit, Praevanit Rangson, Mongkhonmu Srisuchat, Nawa Yukifumi
Department of Helminthology, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand.
Korean J Parasitol. 2010 Sep;48(3):225-9. doi: 10.3347/kjp.2010.48.3.225. Epub 2010 Sep 16.
The aim of this study is to clarify the clinical features of Haplorchis taichui infection in humans in Nan Province, Thailand, and to correlate the clinical features with irritable bowel syndrome (IBS)-like symptoms. In this study area, only H. taichui, but neither other minute intestinal flukes nor small liver flukes were endemic. The degree of infection was determined by fecal egg counts and also by collecting adult worms after deworming. The signs and symptoms of individual patients together with their hematological and biochemical laboratory data were gathered to evaluate the relationship between the clinical features and the severity of infection. Special emphasis was made to elucidate the possible similarities of the clinical features of H. taichui infection and IBS-like symptoms. The results showed useful clinical information and the significant (> 50%) proportion of haplorchiasis patients complained of abdominal pain, lassitude, and flatulence, which were the important diagnostic symptoms of IBS. This study has reported a possible link between H. taichui and IBS, and H. taichui might probably play a role in the etiology of these IBS-like symptoms.
本研究的目的是阐明泰国难府人体感染泰国棘隙吸虫的临床特征，并将这些临床特征与肠易激综合征（IBS）样症状相关联。在本研究区域，仅泰国棘隙吸虫为地方流行，其他微小肠吸虫及小型肝吸虫均无地方流行。通过粪便虫卵计数以及驱虫后收集成虫来确定感染程度。收集个体患者的体征和症状以及他们的血液学和生化实验室数据，以评估临床特征与感染严重程度之间的关系。特别强调阐明泰国棘隙吸虫感染的临床特征与IBS样症状可能存在的相似性。结果显示了有用的临床信息，并且相当比例（>50%）的棘口吸虫病患者主诉腹痛、乏力和肠胃胀气，这些是IBS的重要诊断症状。本研究报告了泰国棘隙吸虫与IBS之间可能存在的联系，并且泰国棘隙吸虫可能在这些IBS样症状的病因中起作用。
