舒尼替尼相关坏疽性脓皮病的第二例病例。
A Second Case of Sunitinib-associated Pyoderma Gangrenosum.
作者信息
Dean Steven M, Zirwas Matthew
机构信息
The Ohio State University, Columbus, Ohio.
出版信息
J Clin Aesthet Dermatol. 2010 Aug;3(8):34-5.
Abstract
Pyoderma gangrenosum is a painful, noninfectious, ulcerative, cutaneous disorder that most commonly affects the lower extremities. The diagnosis is made by recognizing the characteristic clinical manifestations in the setting of a causative systemic disease and excluding other causes of similar-appearing ulcerations. Pyoderma gangrenosum often evolves in the setting of systemic illnesses, such as inflammatory bowel disease, rheumatological disorders, and hematological conditions. However, several medications have rarely been linked to pyoderma gangrenosum. The authors report the second case of sunitinib-associated pyoderma gangrenosum in a 61-year-old patient with recurrent renal cell carcinoma.
摘要
坏疽性脓皮病是一种疼痛性、非感染性、溃疡性皮肤疾病，最常累及下肢。诊断需在存在致病系统性疾病的情况下识别特征性临床表现，并排除其他外观相似溃疡的病因。坏疽性脓皮病常发生于系统性疾病背景下，如炎症性肠病、风湿性疾病和血液系统疾病。然而，有几种药物很少与坏疽性脓皮病相关。作者报告了第二例与舒尼替尼相关的坏疽性脓皮病病例，患者为一名61岁复发性肾细胞癌患者。
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