一例非典型坏疽性脓皮病。
A case of atypical pyoderma gangrenosum.
作者信息
Vasili Ermira, Shkodrani Entela, Labinoti Liberta, Xhaja Alert
机构信息
Clinic of Dermatology, University Hospital Center "Mother Theresa", Tirane, Albania.
出版信息
J Dermatol Case Rep. 2010 Apr 11;4(1):18-21. doi: 10.3315/jdcr.2010.1044.
BACKGROUND
Pyoderma gangrenosum is a rare inflammatory disease of unknown etiology and unspecific histopathology. There are no clear-cut criteria for the diagnosis of this disease. The diagnosis is usually made based on clinical appereance, course of disease and possible, commonly coexisting disorders. In atypical cases the diagnosis is based on exclusion of other causes of similar appearing cutaneous ulcerations.
MAIN OBSERVATIONS
The 67-year-old male patient, presented with a 15-year history of painful ulcers and vegetative lesions covered with sero-hemorrhagic and purulent secretions, localized on the dorsal surface of both hands leading to self-amputation of distal phalanges. We report a step-by-step The patient refers to have these complaints for more than 15 years. An extensive diagnostic procedure led to the diagnosis of pyoderma gangrenosum as a diagnosis of exclusion.
CONCLUSION
This report shows an atypical variant of an ulcerative disease. Pyoderma gangrenosum, a diagnosis of exclusion, was sustained based on an extensive diagnostic procedure. In this article we describe the step-by-step approach which let to this diagnosis.
背景
坏疽性脓皮病是一种病因不明且组织病理学无特异性的罕见炎症性疾病。目前尚无明确的该疾病诊断标准。诊断通常基于临床表现、病程以及可能同时存在的常见疾病。在非典型病例中，诊断基于排除其他导致类似皮肤溃疡表现的病因。
主要观察结果
一名67岁男性患者，有15年疼痛性溃疡和有浆液性出血及脓性分泌物覆盖的增殖性皮损病史，位于双手背，导致远端指骨自截。我们报告了一个逐步诊断过程。患者称有这些症状超过15年。经过广泛的诊断程序后，排除其他疾病，诊断为坏疽性脓皮病。
结论
本报告展示了一种溃疡性疾病的非典型变体。坏疽性脓皮病作为一种排除性诊断，是基于广泛的诊断程序确定的。在本文中，我们描述了得出该诊断的逐步方法。
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