Department of Radiology, Seoul National University Hospital, 28, Yeongon-dong, Jongno-gu, Seoul, 110-744, Korea.
Int J Cardiovasc Imaging. 2010 Dec;26(Suppl 2):303-10. doi: 10.1007/s10554-010-9713-1. Epub 2010 Sep 28.
To evaluate the diagnostic accuracy of multidetector computed tomography (MDCT) angiography for prediction of availability of the right gastroepiploic artery (RGEA) for coronary artery bypass grafting surgery (CABG). This study included 149 patients who underwent both preoperative MDCT angiography and exploratory laparotomy to harvest the RGEA for CABG. The prediction of availability of RGEA using the MDCT finding was evaluated by comparing it to an exploratory laparotomy evaluation of RGEA as a gold standard. The MDCT findings of atherosclerosis and diameter of the RGEA were analyzed. The atherosclerosis of other visceral branches was also analyzed for the detection of affecting factors to the availability for CABG. Atherosclerotic change of vessel was defined as findings including vessel wall calcification, luminal irregularity, aneurysmal change, and apparent atheroma. For statistical analysis, unpaired t-test and receiver operating curve analyses were used to compare the size of the RGEA, and the chi-square test was used to evaluate significant determinant factors of RGEA availability. In exploratory laparotomy, 21 out of 149 RGEAs were classified as inappropriate as a graft for CABG. The reason for inappropriateness was atherosclerosis of RGEA in 15 patients and small diameter in six patients. Sensitivity, specificity, positive predictive value and negative predictive value of MDCT angiography for assessing RGEA atherosclerosis was 60, 99.6, 94.7 and 96.1%, respectively. Atherosclerotic change of the RGEA itself was the only significant determinant factor for predicting the appropriateness of each RGEA. The mean diameter was 1.94 mm in 21 inappropriate RGEAs and 2.41 mm in 128 appropriate RGEAs. This difference was significant (P = 0.001). The least diameter of appropriate RGEA was 1.4 mm on MDCT angiography, and the cut-off value determined by ROC analysis was 1.8 mm with 82.8% of sensitivity and 61.9% of specificity for inappropriate RGEA, and the area under the curve value was 0.729. MDCT is useful preoperative evaluation tool for RGEA availability. Findings of atherosclerosis of the RGEA and a small diameter on MDCT angiography suggest inappropriateness of the RGEA for CABG surgery.
评估多排螺旋 CT 血管造影(MDCTA)对预测右胃网膜动脉(RGEA)用于冠状动脉旁路移植术(CABG)的可用性的诊断准确性。这项研究包括 149 名患者,他们都接受了术前 MDCTA 和剖腹探查术以获取 RGEA 用于 CABG。通过将 MDCT 发现与剖腹探查术评估 RGEA 作为金标准进行比较,评估了 RGEA 可用性的 MDCT 发现的预测。分析了 RGEA 的动脉粥样硬化和直径的 MDCT 表现。还分析了其他内脏分支的动脉粥样硬化,以检测影响 CABG 可用性的因素。血管的动脉粥样硬化改变被定义为包括血管壁钙化、管腔不规则、动脉瘤样改变和明显的动脉粥样斑块等发现。进行统计学分析时,使用了配对 t 检验和接收者操作特征曲线分析来比较 RGEA 的大小,并使用卡方检验来评估 RGEA 可用性的显著决定因素。在剖腹探查术中,149 个 RGEA 中有 21 个被归类为不适合 CABG 移植物。不适合的原因是 15 名患者的 RGEA 动脉粥样硬化和 6 名患者的小直径。MDCTA 评估 RGEA 动脉粥样硬化的敏感性、特异性、阳性预测值和阴性预测值分别为 60%、99.6%、94.7%和 96.1%。RGEA 本身的动脉粥样硬化改变是预测每个 RGEA 适宜性的唯一显著决定因素。21 个不合适的 RGEA 的平均直径为 1.94 毫米,128 个合适的 RGEA 的平均直径为 2.41 毫米。这一差异具有统计学意义(P=0.001)。在 MDCTA 上,合适的 RGEA 的最小直径为 1.4 毫米,ROC 分析确定的截断值为 1.8 毫米,对不合适的 RGEA 的敏感性为 82.8%,特异性为 61.9%,曲线下面积值为 0.729。MDCT 是 RGEA 可用性的有用术前评估工具。RGEA 的动脉粥样硬化和 MDCTA 上的小直径表现表明 RGEA 不适合 CABG 手术。