Division of Orthopaedic Surgery, Mount Sinai Hospital, 600 University Avenue, Suite 476A, Toronto, ON, M5G 1X5, Canada.
Clin Orthop Relat Res. 2010 Dec;468(12):3295-303. doi: 10.1007/s11999-010-1591-2.
While acetabular structural allografts provide an important alternative for reconstructions, concerns remain with long-term graft resorption, collapse, and failure. Midterm studies of minor column (shelf) allograft suggest reasonable survival but long-term survival is unknown.
QUESTIONS/PURPOSES: We therefore assessed long-term graft/cup survivorship, functional scores, radiographic resorption, and complications associated with minor column allograft.
We retrospectively reviewed 74 patients (85 hips) with a mean age of 54 years (range, 28-83 years) undergoing acetabular cup revision using a minor column allograft. A minor column allograft was used in uncontained acetabular bone defects sized between 30% and 50% of the acetabulum. Graft failure was considered to occur when the graft required revision with another graft, metal augment, reconstruction cage, or excision arthroplasty. The minimum followup was 5 years (mean, 16 years; range, 5.3-25 years).
Twenty-three patients (27 hips) had rerevision for all causes at a mean time to rerevision of 6.9 years (range, 0.1-23). Fifteen grafts failed at a mean time-to-rerevision of 6.1 years (range, 0.5-23.2). The 15- and 20-year Kaplan-Meier survivorships were 61% and 55% for cups and 78% for grafts with rerevision for all causes as end point. With rerevision for aseptic loosening as end point, survivorships were 67% and 61% for cups and 81% for grafts. The mean modified Harris hip scores were 41 (range, 20-60) preoperatively, 73 (range, 40-95) at 1 year postoperatively and 73 (range, 26-93) at last followup.
The data may provide a long-term benchmark by which future treatments for Type III defects can be measured.
虽然髋臼结构性同种异体移植物为重建提供了重要的选择,但仍存在长期移植物吸收、塌陷和失败的问题。关于小柱(货架)同种异体移植物的中期研究表明其具有合理的存活率,但长期存活率尚不清楚。
问题/目的:因此,我们评估了小柱同种异体移植物的长期移植物/杯生存率、功能评分、放射学吸收和相关并发症。
我们回顾性分析了 74 例(85 髋)接受髋臼杯翻修术的患者,平均年龄为 54 岁(范围 28-83 岁),使用小柱同种异体移植物。在髋臼 30%-50%大小的非包容髋臼骨缺损中使用小柱同种异体移植物。当移植物需要用另一个移植物、金属增强物、重建笼或切除关节成形术进行翻修时,认为移植物失败。最低随访时间为 5 年(平均 16 年;范围 5.3-25 年)。
23 例(27 髋)因各种原因再次翻修,平均再次翻修时间为 6.9 年(范围 0.1-23 年)。15 个移植物在平均 6.1 年(范围 0.5-23.2 年)时失败。以所有原因的再次翻修为终点,15 年和 20 年的 Kaplan-Meier 生存率分别为 61%和 55%的髋臼和 78%的移植物。以无菌性松动的再次翻修为终点,髋臼和移植物的生存率分别为 67%和 61%和 81%。术前改良 Harris 髋关节评分平均为 41(范围 20-60),术后 1 年为 73(范围 40-95),末次随访时为 73(范围 26-93)。
这些数据可能为未来 III 型缺陷的治疗提供长期基准。