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翻修髋关节置换术中小柱同种异体移植物的长期结果。

Long-term results for minor column allografts in revision hip arthroplasty.

机构信息

Division of Orthopaedic Surgery, Mount Sinai Hospital, 600 University Avenue, Suite 476A, Toronto, ON, M5G 1X5, Canada.

出版信息

Clin Orthop Relat Res. 2010 Dec;468(12):3295-303. doi: 10.1007/s11999-010-1591-2.

Abstract

BACKGROUND

While acetabular structural allografts provide an important alternative for reconstructions, concerns remain with long-term graft resorption, collapse, and failure. Midterm studies of minor column (shelf) allograft suggest reasonable survival but long-term survival is unknown.

QUESTIONS/PURPOSES: We therefore assessed long-term graft/cup survivorship, functional scores, radiographic resorption, and complications associated with minor column allograft.

METHODS

We retrospectively reviewed 74 patients (85 hips) with a mean age of 54 years (range, 28-83 years) undergoing acetabular cup revision using a minor column allograft. A minor column allograft was used in uncontained acetabular bone defects sized between 30% and 50% of the acetabulum. Graft failure was considered to occur when the graft required revision with another graft, metal augment, reconstruction cage, or excision arthroplasty. The minimum followup was 5 years (mean, 16 years; range, 5.3-25 years).

RESULTS

Twenty-three patients (27 hips) had rerevision for all causes at a mean time to rerevision of 6.9 years (range, 0.1-23). Fifteen grafts failed at a mean time-to-rerevision of 6.1 years (range, 0.5-23.2). The 15- and 20-year Kaplan-Meier survivorships were 61% and 55% for cups and 78% for grafts with rerevision for all causes as end point. With rerevision for aseptic loosening as end point, survivorships were 67% and 61% for cups and 81% for grafts. The mean modified Harris hip scores were 41 (range, 20-60) preoperatively, 73 (range, 40-95) at 1 year postoperatively and 73 (range, 26-93) at last followup.

CONCLUSION

The data may provide a long-term benchmark by which future treatments for Type III defects can be measured.

摘要

背景

虽然髋臼结构性同种异体移植物为重建提供了重要的选择,但仍存在长期移植物吸收、塌陷和失败的问题。关于小柱(货架)同种异体移植物的中期研究表明其具有合理的存活率,但长期存活率尚不清楚。

问题/目的:因此,我们评估了小柱同种异体移植物的长期移植物/杯生存率、功能评分、放射学吸收和相关并发症。

方法

我们回顾性分析了 74 例(85 髋)接受髋臼杯翻修术的患者,平均年龄为 54 岁(范围 28-83 岁),使用小柱同种异体移植物。在髋臼 30%-50%大小的非包容髋臼骨缺损中使用小柱同种异体移植物。当移植物需要用另一个移植物、金属增强物、重建笼或切除关节成形术进行翻修时,认为移植物失败。最低随访时间为 5 年(平均 16 年;范围 5.3-25 年)。

结果

23 例(27 髋)因各种原因再次翻修,平均再次翻修时间为 6.9 年(范围 0.1-23 年)。15 个移植物在平均 6.1 年(范围 0.5-23.2 年)时失败。以所有原因的再次翻修为终点,15 年和 20 年的 Kaplan-Meier 生存率分别为 61%和 55%的髋臼和 78%的移植物。以无菌性松动的再次翻修为终点,髋臼和移植物的生存率分别为 67%和 61%和 81%。术前改良 Harris 髋关节评分平均为 41(范围 20-60),术后 1 年为 73(范围 40-95),末次随访时为 73(范围 26-93)。

结论

这些数据可能为未来 III 型缺陷的治疗提供长期基准。

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