Department of Obstetrics and Gynecology, Cheil General Hospital and Women's Healthcare Center, University of Kwandong, 1-19 Mukjeong-dong, Jung-gu, Seoul 100-380, Korea.
Int J Clin Oncol. 2011 Feb;16(1):45-9. doi: 10.1007/s10147-010-0128-8. Epub 2010 Sep 29.
The aim of this study was to evaluate the clinical and pathological features of a rare tumor, primary fallopian tube carcinoma (PFTC).
We retrospectively analyzed the medical records of 26 patients who were diagnosed with PFTC at Cheil General Hospital and Women's Healthcare Center between March 1992 and November 2009.
Median patient age was 54.6 (range 41-69) years, and the mean follow-up period was 59.8 (range 3-200) months. Twenty-one (80.8%) patients had one or more of the following preoperative symptoms: vaginal bleeding, abdominal pain, or a palpable mass. No patient was diagnosed with PFTC preoperatively; 17 (65.4%) patients were diagnosed as having an adnexal mass, six (23.1%) had hydrosalpinx, and three (11.5%) had coexisting endometrial pathology. In seven (26.9%) cases, PFTC was missed during the operation, so an additional surgery was later performed. Ten (38.5%) patients were in stage I, two (7.7%) in stage II, 13 (50%) in stage III, and one (3.8%) in stage IV. The serous type was histologically predominant (76.9%), and most were high grade (76.9%). The 5-year survival rate was 81.7%.
Primary fallopian tube carcinoma is hardly ever diagnosed preoperatively or intraoperatively due to its rarity. Our report may help surgeons by providing more information about the clinicopathological behavior of PTFC so that patients can be appropriately counseled. Further clinical studies should be performed to collect more information about this rare tumor.
本研究旨在评估一种罕见肿瘤——原发性输卵管癌（PFTC）的临床和病理特征。
我们回顾性分析了 1992 年 3 月至 2009 年 11 月期间在 Cheil 综合医院和妇女保健中心被诊断为 PFTC 的 26 例患者的病历。
中位患者年龄为 54.6 岁（范围 41-69 岁），平均随访时间为 59.8 个月（范围 3-200 个月）。21 例（80.8%）患者有以下一种或多种术前症状：阴道出血、腹痛或可触及的肿块。没有患者在术前被诊断为 PFTC；17 例（65.4%）患者被诊断为附件肿块，6 例（23.1%）为输卵管积水，3 例（11.5%）为并存子宫内膜病变。在 7 例（26.9%）病例中，PFTC 在手术中被遗漏，因此后来进行了额外的手术。10 例（38.5%）患者为 I 期，2 例（7.7%）为 II 期，13 例（50%）为 III 期，1 例（3.8%）为 IV 期。组织学上以浆液型为主（76.9%），且多数为高级别（76.9%）。5 年生存率为 81.7%。
由于其罕见性，原发性输卵管癌在术前或术中几乎从未被诊断过。我们的报告可能通过提供更多关于 PFTC 的临床病理行为的信息来帮助外科医生，以便对患者进行适当的咨询。应进行进一步的临床研究，以收集更多关于这种罕见肿瘤的信息。
