胃肠道间质瘤伴早期颅内侵犯的不典型表现。
Unusual presentation of gastrointestinal stromal tumor with early cerebral involvement.
机构信息
Department of Oncology, Bon Secours Hospital, Cork, Republic of Ireland.
出版信息
Ir J Med Sci. 2011 Sep;180(3):765-6. doi: 10.1007/s11845-010-0591-2. Epub 2010 Sep 30.
PMID:20878498
Abstract
Gastrointestinal stromal tumor (GIST) is a rare tumor typically arising from gastrointestinal tract. GIST very rarely metastasizes beyond abdominal cavity. Metastatic spread to the brain is anecdotal. This is a case study describing metastatic GIST with early cerebral involvement and resistance to therapy with KIT tyrosine kinase inhibitor imatinib mesylate.
摘要
胃肠道间质瘤（GIST）是一种罕见的肿瘤，通常起源于胃肠道。GIST 很少转移到腹腔以外的部位。转移到大脑的情况是偶发的。这是一个病例研究，描述了具有早期脑受累和对 KIT 酪氨酸激酶抑制剂甲磺酸伊马替尼治疗耐药的转移性 GIST。
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