[小鼠129畸胎癌细胞系中鼠C型内源性病毒的表达]

[Murine type C endogenous virus expression in murine 129 teratocarcinoma cell line].

作者信息

Emanoil-Ravicovitch R, Robert J, Canivet M, D'Auriol L, Périès J

出版信息

C R Acad Hebd Seances Acad Sci D. 1978 May 2;286(17):1277-80.

PMID:208797

Abstract

Murine type C viral information is detectable in the cellular genome of both differentiated and undifferentiated cell lines derived from 129 Mouse teratocarcinoma. Cytoplasmic RNA expression which is negligible in differentiated cells, is significantly higher in multipotential undifferentiated cells. Furthermore it was observed that in vitro differentiation of multipotent cells leads to a decrease of this expression.

摘要

在源自129小鼠畸胎瘤的分化和未分化细胞系的细胞基因组中可检测到鼠C型病毒信息。在分化细胞中可忽略不计的细胞质RNA表达，在多能未分化细胞中显著更高。此外，观察到多能细胞的体外分化导致这种表达的降低。