全身热疗联合腹腔内顺铂治疗残余卵巢癌

Whole body hyperthermia and intraperitoneal carboplatin in residual ovarian cancer.

作者信息

Cohen J D, Robins H I

机构信息

Department of Human Oncology, University of Wisconsin, Madison 53792.

出版信息

Adv Exp Med Biol. 1990;267:197-202. doi: 10.1007/978-1-4684-5766-7_18.

DOI:10.1007/978-1-4684-5766-7_18

PMID:2088035

Abstract

Intraperitoneal (IP) cisplatin-based chemotherapy provides prolonged disease-free survival in some women with residual peritoneal ovarian cancer following systemic chemotherapy. This review presents several considerations which support the combined use of IP carboplatin and whole body hyperthermia in this patient population. This novel treatment approach is predicated on projected advantages which relate to improved therapeutic index.

摘要

基于顺铂的腹腔内（IP）化疗可使部分接受全身化疗后仍有残留腹膜卵巢癌的女性患者的无病生存期延长。本综述提出了一些支持在该患者群体中联合使用腹腔内卡铂和全身热疗的考虑因素。这种新的治疗方法基于与改善治疗指数相关的预期优势。