Tang Jin, Guo Wei-chun, Yu Ling, Zhao Sheng-hao
Department of Orthopaedics, Renmin Hospital of Wuhan University, Wuhan 430060, China.
Chin J Traumatol. 2010 Oct 1;13(5):289-92.
To observe the clinical efficacy of artificial skin combined with vacuum sealing drainage (VSD) in treating large-area skin defects.
Totally 18 patients with skin defects, treated with artificial skin combined with VSD from September 2008 to May 2009 in our hospital, were retrospectively analyzed in this study. There were 15 males and 3 females, aged 7-66 years, 34.3 years on average. Among them, 10 cases had skin laceration caused by traffic accidents (7 with open fractures), 1 mangled injury, 1 blast injury, 1 stump infection combined with skin defects after amputation and 5 heel ulcers.
All skin grafts in 16 cases survived after being controlled by VSD for one time. For the rest 2 patients, one with skin avulsion on the left foot was given median thickness skin grafts after three times of VSD, the other with open fractures in the left tibia and fibula caused by a traffic accident was given free flap transplantation. Skin grafts of both patients survived, with normal color and rich blood supply.
Skin grafting in conjunction with artificial skin and VSD is much more effective than traditional dressing treatment and worth wide application in clinic.
观察人工皮肤联合封闭式负压引流（VSD）治疗大面积皮肤缺损的临床疗效。
回顾性分析2008年9月至2009年5月在我院采用人工皮肤联合VSD治疗的18例皮肤缺损患者。其中男性15例，女性3例，年龄7 - 66岁，平均34.3岁。其中，交通事故致皮肤裂伤10例（7例合并开放性骨折），碾压伤1例，爆炸伤1例，截肢术后残端感染合并皮肤缺损1例，足跟溃疡5例。
16例患者经一次VSD控制后植皮全部成活。其余2例患者，1例左足皮肤撕脱伤经3次VSD后行中厚皮片移植，另1例因交通事故致左胫腓骨开放性骨折行游离皮瓣移植。2例患者植皮均成活，皮色正常，血运丰富。
人工皮肤联合VSD植皮治疗较传统换药治疗效果显著，值得临床推广应用。
