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肢体膝关节以下大面积软组织缺损的负压封闭引流联合游离皮瓣移植序贯治疗

Sequential therapy of vacuum sealing drainage and free-flap transplantation for children with extensive soft-tissue defects below the knee in the extremities.

机构信息

Department of Orthopaedics and Traumatology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, PR China.

出版信息

Injury. 2012 Jun;43(6):822-8. doi: 10.1016/j.injury.2011.09.031. Epub 2011 Nov 8.

Abstract

PURPOSE

The aim of the study is to evaluate the surgical technique and clinical significance of the sequential therapy of vacuum sealing drainage (VSD) and free-flap transplantation for children with extensive soft-tissue defects below the knee in the extremities.

METHODS

Twenty-two children (aged from 3 to 10 years) received sequential therapy of VSD and free-flap transplantation. All cases suffered from extensive area soft-tissue defects and exposure or partial defects of bones, tendons and other deep tissues. The wound sizes varied from 10 cm × 6 cm to 30 cm × 22 cm. Amongst 22 cases, 12 cases had fresh wounds and the remaining 10 children had necrotising infection. After complete debridement, the wounds were covered by VSD. External fixation or Kirschner-wire fixation should be performed for the cases complicated by unsteady fractures. After the removal of negative pressure VSD devices, free-flap transplantations were performed in 8 cases after debridement, and 14 cases received combined therapy of free-flap transplantation and skin grafting depending upon the severity of soft-tissue and deep-tissue defects. The flap survival and wound healing were followed up postoperatively.

RESULTS

After VSD treatment, the infection of deep-tissue exposure was effectively prevented, and granulation tissues surrounding the exposed areas of tendons and bones grew well. All patients who received free-flap transplantation at the second stage survived without the occurrence of vascular crisis, infection or sinus formation. During follow-up ranging from 6 to 24 months, all the patients were satisfied with the morphological appearance and functional recovery of the affected limbs.

CONCLUSION

Sequential therapy of VSD and free-flap transplantation can serve as a reliable option for children with extensive soft-tissue defects below the knee in the extremities and exposed deep tissues, after complete debridement, which significantly shortens remedy period, enhances success rate for surgery and achieves maximal restoration of limb function.

摘要

目的

本研究旨在评估负压封闭引流(VSD)与游离皮瓣移植序贯治疗儿童下肢大面积软组织缺损伴深部组织外露或部分缺损的手术技术及临床意义。

方法

22 例儿童(年龄 310 岁)接受 VSD 与游离皮瓣移植序贯治疗。所有患者均为大面积软组织缺损伴骨、肌腱等深部组织外露或部分缺损,创面大小为 10 cm×6 cm30 cm×22 cm。22 例中新鲜创面 12 例,坏死感染创面 10 例。彻底清创后,创面采用 VSD 覆盖,合并不稳定骨折者行外固定或克氏针固定。负压封闭引流装置去除后,8 例行清创后游离皮瓣移植,14 例根据软组织及深部组织缺损程度行游离皮瓣移植联合植皮治疗。术后随访皮瓣存活及创面愈合情况。

结果

VSD 治疗后,有效预防了深部组织外露感染,肌腱和骨外露区域周围的肉芽组织生长良好。二期行游离皮瓣移植的所有患者皮瓣均存活,未发生血管危象、感染或窦道形成。随访 6~24 个月,所有患者均对患侧肢体的形态外观和功能恢复满意。

结论

彻底清创后,VSD 与游离皮瓣移植序贯治疗可为儿童下肢大面积软组织缺损伴深部组织外露提供可靠的治疗选择,可明显缩短疗程,提高手术成功率,最大限度地恢复肢体功能。

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