Pace M, Bini M, Millanta L
1st Surgical Clinic, University of Florence, Italy.
Adv Exp Med Biol. 1990;267:297-303. doi: 10.1007/978-1-4684-5766-7_28.
The evaluation of the clinical results in experimental applications of local electromagnetic hyperthermia requires strict control of the physical parameters of the treatment and adhesion to close medical protocols. Development and application processes in close cooperation between physicians and electromagnetic experts are reported and discussed, on the basis of experimental and theoretical research work. Attention is concentrated on a 434 MHz apparatus, where the fundamental physical limits have been identified and the operating features in the clinical practice have been evaluated. The cases eligible for treatment were chosen according basically to the limitations posed by depth, volume and steep temperature gradients. Several cases are reported mainly in association with radiotherapy. Lines of technical improvement are suggested, mainly based on the development and optimization of lower-frequency applicators.
在局部电磁热疗的实验应用中评估临床结果，需要严格控制治疗的物理参数并严格遵循密切的医疗方案。在实验和理论研究工作的基础上，报告并讨论了医生与电磁专家密切合作的开发和应用过程。重点关注一台434兆赫的设备，在该设备中已经确定了基本物理极限，并评估了其临床实践中的操作特性。适合治疗的病例基本上是根据深度、体积和陡峭温度梯度所带来的限制来选择的。报告了几例主要与放射治疗相关的病例。提出了技术改进方向，主要基于低频 applicator 的开发和优化。
