Chavrier C
Faculté d'Odontologie, Laboratoire d'Histo-Physiologie et de Pathologie des Tissus Parodontaux, France.
Arch Oral Biol. 1990;35 Suppl:223S-225S. doi: 10.1016/0003-9969(90)90163-5.
In human gingiva, the elastic system fibres, namely oxytalan, elaunin and elastic fibres, are distributed in the upper, medium and deep layers of gingival connective tissue, respectively. They are formed by a microfibrillar and an amorphous component characterized as elastin. In the gingival connective tissue fibroblastic cells are likely to be the main source of production of elastin in the extracellular matrix. Elastin is secreted as a soluble precursor (tropoelastin), which spontaneously forms insoluble aggregates of elastin. Elastin is then laid down at the surface of the microfibrillar component, which could serve as a site for deposition of elastin during elastogenesis, and subsequently be incorporated in an amorphous area to form elaunin and elastic fibres.
在人类牙龈中,弹性系统纤维,即耐酸性纤维、弹力素和弹性纤维,分别分布在牙龈结缔组织的上层、中层和深层。它们由微原纤维和一种被称为弹性蛋白的无定形成分构成。在牙龈结缔组织中,成纤维细胞可能是细胞外基质中弹性蛋白的主要产生来源。弹性蛋白作为一种可溶性前体(原弹性蛋白)分泌出来,它会自发形成不溶性的弹性蛋白聚集体。然后弹性蛋白沉积在微原纤维成分的表面,在弹性蛋白生成过程中,微原纤维成分可作为弹性蛋白沉积的位点,随后被并入无定形区域以形成弹力素和弹性纤维。