Direct evidence for separate binding sites for L-Glu and amino acid feedback inhibitors on unadenylylated glutamine synthetase from E. coli. - Suppr | 超能文献

Direct evidence for separate binding sites for L-Glu and amino acid feedback inhibitors on unadenylylated glutamine synthetase from E. coli.

作者信息

Rhee S G, Villafranca J J, Chock P B, Stadtman E R

出版信息

Biochem Biophys Res Commun. 1977 Sep 9;78(1):244-50. doi: 10.1016/0006-291x(77)91246-3.

DOI:10.1016/0006-291x(77)91246-3

PMID:20883

Abstract

摘要

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Regulation of Escherichia coli glutamine synthetase. Evidence for the action of some feedback modifiers at the active site of the unadenylylated enzyme.大肠杆菌谷氨酰胺合成酶的调控。关于一些反馈调节因子在未腺苷酸化酶活性位点作用的证据。

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Feedback inhibition of fully unadenylylated glutamine synthetase from Salmonella typhimurium by glycine, alanine, and serine.鼠伤寒沙门氏菌完全未腺苷酸化的谷氨酰胺合成酶受甘氨酸、丙氨酸和丝氨酸的反馈抑制。

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Topographical analysis of regulatory and metal ion binding sites on glutamine synthetase from Escherichia coli: 13C and 31P nuclear magnetic resonance and fluorescence energy transfer study.大肠杆菌谷氨酰胺合成酶上调控位点和金属离子结合位点的拓扑分析：13C和31P核磁共振及荧光能量转移研究

Proc Natl Acad Sci U S A. 1978 Mar;75(3):1255-9. doi: 10.1073/pnas.75.3.1255.