Paediatric Dental Sedation, Department of Paediatric Dentistry, King's College Hospital, Camberwell, London, UK.
Br Dent J. 2010 Oct 9;209(7):E12. doi: 10.1038/sj.bdj.2010.886. Epub 2010 Oct 1.
Conscious sedation for young children is a rapidly developing area of clinical activity. Many studies have shown positive results using oral midazolam on children. These case series investigated oral midazolam conscious sedation as an alternative to general anaesthesia in a clinical service setting.
The purpose of this work was to determine the safety and efficacy of oral midazolam for conscious sedation in children undergoing dental treatment.
Patients were selected by colleagues for treatment under oral sedation. The main general criteria were weight below 36 kilos and ASA I, II, or III. Midazolam 0.5 mg/kg was administered orally. A pulse oximeter was applied to a finger to monitor vital signs and the Houpt scale was used to assess behaviour.
A total of 510 children aged between 13 months and 11 years were included. The behaviour of 379 (74%) was excellent or very good. The pulse rate and peripheral oxygenation were within the normal range for all patients. The main adverse effects were diplopia and post-sedation dysphoria.
Oral midazolam is a safe and effective method of sedation although some children were agitated and distressed either during or after treatment. Parents need to be warned about this.
小儿清醒镇静是临床活动中一个快速发展的领域。许多研究表明,口服咪达唑仑对儿童有积极的效果。这些病例系列研究调查了口服咪达唑仑清醒镇静作为全麻替代方案在临床服务环境中的应用。
本研究旨在确定口服咪达唑仑在接受牙科治疗的儿童中进行清醒镇静的安全性和有效性。
同事选择患者进行口服镇静治疗。主要的一般标准是体重低于 36 公斤和 ASA I、II 或 III 级。给予 0.5mg/kg 咪达唑仑口服。通过手指上的脉搏血氧仪监测生命体征,使用 Houpt 量表评估行为。
共纳入 510 名年龄在 13 个月至 11 岁之间的儿童。379 名(74%)的行为表现优秀或非常好。所有患者的脉搏率和外周氧饱和度均在正常范围内。主要的不良反应是复视和镇静后烦躁不安。
口服咪达唑仑是一种安全有效的镇静方法,但有些儿童在治疗过程中或治疗后会感到激动和不适。家长需要对此有所了解。