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跨越治疗:反思一种适应于抑郁的甲基苯丙胺使用者的治疗策略。

Stepping through treatment: reflections on an adaptive treatment strategy among methamphetamine users with depression.

机构信息

National Drug and Alcohol Research Centre, University of New South Wales, New South Wales, Australia.

出版信息

Drug Alcohol Rev. 2010 Sep;29(5):475-82. doi: 10.1111/j.1465-3362.2010.00203.x.

Abstract

INTRODUCTION AND AIMS

Stepped-care has been recommended in the alcohol and other drug field and adopted in a number of service settings, but few research projects have examined this approach. This article aims to describe a pilot trial of stepped-care methods in the treatment of methamphetamine use and depression comorbidity.

DESIGN AND METHODS

An adaptive treatment strategy was developed based on recommendations for stepped-care among methamphetamine users, and incorporating cognitive behaviour therapy/motivational intervention for methamphetamine use and depression. The adaptive treatment strategy was compared with a fixed treatment, comprising an extended integrated cognitive behaviour therapy/motivational intervention treatment. Eighteen participants across two study sites were involved in the trial, and were current users of methamphetamines (at least once weekly) exhibiting at least moderate symptoms of depression (score of 17 or greater on the Beck Depression Inventory II).

RESULTS

Treatment delivered via the adaptive treatment (stepped-care) model was associated with improvement in depression and methamphetamine use, however, was not associated with more efficient delivery of psychological treatment to this population relative to the comparison treatment.

DISCUSSION AND CONCLUSIONS

This pilot trial attests to the potential for adaptive treatment strategies to increase the evidence base for stepped-care approaches within the alcohol and other drug field. However, in order for stepped-care treatment in this trial to be delivered efficiently, specific training in the delivery and philosophy of the model is required.

摘要

介绍和目的

阶梯式护理已在酒精和其他药物领域得到推荐,并在许多服务环境中得到采用,但很少有研究项目对此方法进行了研究。本文旨在描述一项针对治疗甲基苯丙胺使用和抑郁共病的阶梯式护理方法的试点试验。

设计和方法

根据针对甲基苯丙胺使用者的阶梯式护理建议,并结合针对甲基苯丙胺使用和抑郁的认知行为疗法/动机干预,制定了适应性治疗策略。适应性治疗策略与固定治疗(包括扩展的综合认知行为疗法/动机干预治疗)进行了比较。该试验涉及两个研究地点的 18 名参与者,他们目前是甲基苯丙胺使用者(每周至少一次),表现出至少中度的抑郁症状(贝克抑郁量表 II 得分 17 或更高)。

结果

通过适应性治疗(阶梯式护理)模型提供的治疗与抑郁和甲基苯丙胺使用的改善相关,但与比较治疗相比,并未与该人群中更有效地提供心理治疗相关。

讨论和结论

这项试点试验证明了适应性治疗策略有可能增加酒精和其他药物领域中阶梯式护理方法的证据基础。然而,为了使该试验中的阶梯式护理治疗能够有效地提供,需要对模型的交付和哲学进行特定的培训。

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