MicroRNAs 与细胞表型。
MicroRNAs and cellular phenotypy.
机构信息
Neuroscience Research Institute, Department of Molecular Cellular Developmental Biology, University of California, Santa Barbara, Santa Barbara, CA 93106, USA.
出版信息
Cell. 2010 Oct 1;143(1):21-6. doi: 10.1016/j.cell.2010.09.008.
PMID:20887887
Abstract
This Essay explores the notion that specialized cells have unique vulnerabilities to environmental contingencies that microRNAs help to counteract. Given the ease with which new microRNAs evolve, they may serve as ideal facilitators for the emergence of new cell types.
摘要
本文探讨了这样一种观点，即专门化细胞对环境因素具有独特的脆弱性，而 microRNAs 有助于对抗这种脆弱性。鉴于新的 microRNAs 很容易进化，它们可能是新细胞类型出现的理想促进剂。
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