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儿童光感性测试。

Photosensitivity testing in children.

机构信息

Department of Dermatology/Allergology/Venereology, University Medical Center Utrecht, Utrecht, The Netherlands.

出版信息

J Am Acad Dermatol. 2010 Dec;63(6):1019-25. doi: 10.1016/j.jaad.2009.12.032.

DOI:10.1016/j.jaad.2009.12.032
PMID:20889233
Abstract

BACKGROUND

Phototesting is an important diagnostic tool to objectify light-related symptoms. Data on phototesting procedures in children are scarce.

OBJECTIVE

The aim of this study was to evaluate phototest results in photosensitivity disorders in children.

METHODS

The phototest procedures are described. All children phototested in our department between 1995 and 2007 were included in this retrospective study. Children given the diagnosis of polymorphic light eruption (PLE) were selected for follow-up.

RESULTS

A total of 92 children (39 boys and 53 girls, age range 4-16 years) were successfully phototested. A photosensitivity disorder was confirmed in 56 children (61%, 24 boys and 32 girls). PLE was diagnosed in 39%, photosensitivity associated with atopic dermatitis in 23%, and erythropoietic protoporphyria in 23%. Other diagnoses were less common. Ten children with PLE were followed up for at least 5 years. Seven reported their photosensitivity had not changed over time, in two cases it had diminished, and in one patient the photosensitivity had disappeared.

LIMITATIONS

Retrospective study design is a limitation.

CONCLUSION

Phototesting in children is feasible when performed in a case- and child-dependent manner. PLE was the most prevalent diagnosis in our series followed by photosensitivity in atopic dermatitis.

摘要

背景

光测试是客观化与光相关症状的重要诊断工具。儿童光测试程序的数据很少。

目的

本研究旨在评估儿童光敏性疾病的光测试结果。

方法

描述了光测试程序。本回顾性研究纳入了 1995 年至 2007 年间在我科进行光测试的所有儿童。对诊断为多形性光疹(PLE)的儿童进行了随访。

结果

共有 92 名儿童(39 名男孩和 53 名女孩,年龄 4-16 岁)成功进行了光测试。56 名儿童(61%,24 名男孩和 32 名女孩)被证实存在光敏性疾病。诊断为 PLE 的占 39%,与特应性皮炎相关的光敏性占 23%,红细胞生成性原卟啉症占 23%。其他诊断较少见。10 名 PLE 患儿至少随访 5 年。7 名患儿报告其光敏性未随时间改变,2 名患儿光敏性减轻,1 名患儿光敏性消失。

局限性

回顾性研究设计是一个局限性。

结论

在儿童中进行光测试是可行的,但需要根据具体情况和儿童情况进行。在我们的系列研究中,最常见的诊断是 PLE,其次是特应性皮炎相关的光敏性。

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