Tufts University School of Medicine, Renal Division, Baystate Medical Center, MA, USA.
Cleve Clin J Med. 2010 Oct;77(10):715-26. doi: 10.3949/ccjm.77a.08051.
Hyponatremia, in its most severe form, requires urgent infusion of hypertonic saline to correct cerebral edema. However, overly rapid correction of chronic hyponatremia can cause osmotic demyelination syndrome. The authors review the treatment of hyponatremia in order to provide clinicians with a sound approach in a variety of settings in which severity, symptoms, and underlying disease states influence therapy. Also discussed is the current role of vasopressin antagonists in treatment.
低钠血症在其最严重的形式下需要紧急输注高渗盐水以纠正脑水肿。然而，过快纠正慢性低钠血症可引起渗透性脱髓鞘综合征。作者综述了低钠血症的治疗方法，以便为临床医生在严重程度、症状和基础疾病状态影响治疗的各种情况下提供合理的方法。还讨论了目前血管加压素拮抗剂在治疗中的作用。
